Comprehensive Handbook of Alcohol Related Pathology

Comprehensive Handbook of Alcohol Related Pathology

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This comprehensive handbook is a "one-stop-shop" for all researchers involved in the field of alcohol-related harm at the whole body or cellular level. Over 100 chapters provide abundant information of a wide range of topics that extend from the evolutionary aspects of alcohol consumption and the prevalence of alcohol misuse to programmed cell death. Each chapter is highly illustrated with tables and figures making this a valuable reference for students, clinicians and researchers alike.
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Product details

  • Hardback | 2192 pages
  • 264.2 x 335.3 x 167.6mm | 5,964.81g
  • Academic Press Inc
  • San Diego, United States
  • English
  • Special ed.
  • 0125643705
  • 9780125643702

Table of contents

Contributors
Preface
Foreword
Volume One
Part I: General Aspects of Alcohol Toxicity, Consumption, and Disease
Evolutionary and Historical Aspects of Ethanol Ingestion
Alcohol Metabolism: General Aspects
Intake of Different Alcoholic Beverages and Life-style and Psychosocial Factors
Genetic Aspects of Alcohol Metabolism: An Overview
Predictors of Alcohol Consumption
Binge Drinking: Patterns, Explanations, and Policy
Breath and Blood Alcohol
Effects of Food and Body Composition on Blood Alcohol Levels
Disposal of Ethanol Carbon Atoms
Effect of Alcohol on Water and Sodium Homeostasis
Energy from Alcohol
The Mediterranean Diet and the Contribution and Role of Alcohol
The Role of Alcohol in Injury Deaths
Death from Alcohol Poisoning
Alcohol and the Workplace
Alcohol Misuse in Adolescents: Epidemiology, Clinical Characteristics,
Diagnosis, and Treatment
Alcohol Misuse in Adolescents: Individual Differences, Prevention,
Identification, and Intervention
What is the Impact of Alcohol on Learning in University Students?
The Relationship Between Alcohol Misuse and the Homelessness
Alcohol and Sport Activities: Spectator's Perspective
Part II: Damage/Disease
General Aspects of Pathology
An Overview of Pathologies Occurring in Alcohol Abusers
Gender Differences in Alcohol Pathology
Psychological Effects of Alcohol Misuse
The Effect of Alcohol on Quality of Life
Alcohol and Road Accidents
Trauma and Alcohol
Clinical Implications of Alcohol Misuse for Surgery
Fetal Alcohol Spectrum Disorder
Nutritional Status in Alcoholics
Alcohol and Body Composition
Beneficial Components of White Wine
Polyphenols and Alcohol: Complementary Mechanisms for the Protective
Effects of Moderate Wine Consumption
Overview of ALDH Polymorphism: Relation to Cardiovascular Effects of Alcohol
Overview on the Effects of Amount and Type of Alcohol on Morbidity and Mortality
Alcohol-related Mortality in Russia
(ii) Organ Damage
Epidemiology and Risk Factors Involved in Alcoholic Liver Disease
Polymorphism and Alcoholic Liver Disease
Liver Injury During Alcohol Use and Withdrawal
Alcohol Consumption and Diabetes Mellitus
Alcoholic Ketoacidosis
Alcohol, Alcoholism and Effects on the Kidney and Kidney Disease
Alcohol Intake and the Lower Urinary Tract
Alcohol and Prostate Cancer
Oral Health and Alcohol

Volume 2
Alcohol and the Gastrointestinal Tract
Alcohol, ALDH2 Genotypes and Intestinal Cancer
Alcohol and Pancreatitis
The Skin and Alcohol
Alcohol, Blood Pressure and Hypertension
Alcohol and Stroke
Alcoholic Cardiomyopathy
Epidemiologic Aspects of ALDH2 Genotypes and Cardiovascular Parameters
Alcoholic Myopathy: Clinical Aspects
Alcohol and the Eye: Friend or Foe
Marchiafava-Bignami Disease in Alcoholism
Peripheral Neuropathy
(iii) Cells, Pathways, Interactions, Processes
Defects in Methionine Metabolism: Its Role in Ethanol-induced Liver Injury
Roles of Kupffer Cells in Alcoholic Liver Disease
The Role of the Stellate Cell in Alcohol Mediated Tissue Injury
The Role of T Lymphocytes in the Pathogenesis of Alcoholic Liver Disease
Oxidative Stress in Alcoholic Liver Disease: Clinical Studies
The Relationship between Alcohol-induced Apoptosis and Oxidative Stress in the Liver
Alcohol and HIV Interactions in the Natural History and Treatment of HIV/AIDS
Alcohol and Hepatitis Virus Interactions in Liver Pathology
Moderate Alcohol and Fibrosis in Chronic Viral Hepatitis
Ethanol-Taurine Interactions in the Brain: Mechanisms and
Pathophysiological Implications
The Effect of Ethanol on Ion Channels in the Brain: A New Look
A Nitric Oxide Signaling Pathway Protects the Developing Brain against
Alcohol-induced Neuronal Death
Signaling Pathways in the Heart and Moderate Alcohol Intake
Effects of Alcohol on Vascular Function
Vascular and Biochemical Effects of Moderate Alcohol Consumption:
Mechanisms of Protection Against Cardiovascular Disease
Alcohol and Xenobiotics in Placenta Damage
Molecular Mechanisms in Fetal Alcohol Syndrome: Shh-signaling
The Process of Bacterial Translocation and Implications for Health in Alcoholics
Alcohol, Altered Gut Permeability, and Endotoxins
Hormonal Responses in Alcoholism
Alcohol-induced Changes in the GH-IGF Axis
Mechanisms in Prostate Damage by Alcohol
Signaling Pathways in Human Breast Cells in Response to Alcohol:
Mechanisms for Alcohol-induced Breast Cancer
The Ubiquitin-Proteasome System in Alcohol-Induced Pathology
Alcohol and Alkylating Agents
DNA Damage Resulting from Alcohol Abuse with Special Reference to the Brain
Purine Metabolism and the Influence of Alcoholic Beverages
The Role of PKC Isozymes in Mediating Responses to Ethanol
Ethanol Modulation of cAMP-dependent Protein Kinase Subunits Activity:
Mechanisms and Functional Consequences
Adhesion Molecules and Alcohol Consumption
Glucose-regulated Stress Proteins (GRPs) and Alcohol
Heat Shock Proteins and Alcohol
Role of Oxidative Stress in Alcohol-Induced Mitochondrial Dysfunction
Alcohol and Apoptosis

Volume 3
Alcohol and Fatty Acid Ethyl Esters
Modification of Proteins by Reactive Ethanol Metabolites: Adduct Structure, Functional and Pathological Consequences
The Effect of Acetaldehyde on Plasma
Autoantibodies in Alcohol-related Tissue Diseases
Alcohol-induced Membrane Damage
Alcohol Abuse and Eating Disorders
The Relationship Between Obesity and Alcoholic Pathology
Protein Deficiency and Alcohol: Interactions and Organ Effects
Tryptophan Metabolism and Alcoholism
Part III: Selective Methods Used in Alcohol Research
Selective Methods Used in Alcohol Research: Screening in Primary Care - Methods
and Approaches
Psychometric Assessment of Alcohol Use
Self-reported Intake of Alcohol: Methods and Approaches
Use of the DSM-IV: Methods and Approaches
The Alcohol-related Problems Survey: Developing and
Testing a Screening Measure for Older Adults
The Rapid Alcohol Problems Screen: Methods and Application
Methods for Determining Blood Alcohol Concentration: Current and
Retrospective
Urinary Markers of Alcohol Consumption
Methods for Measuring Genetic Variations in ADH
and SLDH Loci: A Practical Approach
Histological Localization of Alcohol Dehydrogenase: Methods, Approaches and Applications
Assays for Alcohol and Aldehyde Dehydrogenase: Methods, Approaches and Applications
Detecting ADH and ALDH Enzymes in Cells and Tissues using Western Blotting
Use of Selectively Bred Alcohol-preferring Rats to Study Alcohol
Abuse, Relapse and Craving
Animal Models of Chronic Alcohol-Induced Liver Damage
Acute Ethanol Dosing Regimens: Methods and Approaches
Use of Isolated Cells in the Study of Ethanol-Induced Hepatotoxicity
Animal Models of Fetal Alcohol Syndrome: Methods and Approaches
Genetically Engineered Animals in Alcohol Research
cDNA Arrays in Alcohol-Related Pathology: Methods and Approaches
Practical Methods for Determining mRNA Levels in Alcohol-Exposed
Tissues and Its Application to Experimental Pathology
Diagnosis of Fetal Alcohol Syndrome: Measurement of the Facial Dysmorphology
Nuclear Magnetic Resonance: Methods and Application to Alcohol Effects in the Liver
Index
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Review quote

"...an excellent addition to a reference library and to the field of addictionology."
- DOODY'S (2005)
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About Ronald Ross Watson

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a senior member of King's College London. He is also Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine. Professor Preedy has longstanding academic interests in substance misuse especially in relation to health and well being. He is a member of the Editorial Board of Drug and Alcohol Dependence and a founding member of the Editorial Board of Addiction Biology. In his career Professor Preedy was Reader at the Addictive Behaviour Centre at The University of Roehampton, and also Reader at the School of Pharmacy (now part of University College London; UCL). Professor Preedy is Editor of the influential works The Handbook Of Alcohol Related Pathology, The Neuropathology of Drug Addictions and Substance Misuse and The Handbook of Cannabis and Related Pathologies (all published by Academic Press-Elsevier). Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctoral degree (DSc). Professor Preedy was elected as a Fellow of the Institute of Biology in 1995 and also as a Fellow to the Royal College of Pathologists in 2000. He was then elected as a Fellow of the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health and Hygiene (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes. Ronald Ross Watson, PhD, is a Professor of Health Promotion Sciences at the University of Arizona, Mel and Enid Zuckerman College of Public Health. Dr. Watson began his research in public health at the Harvard School of Public Health as a fellow in 1971 doing field work on vaccines in Saudi Arabia. He has done clinical studies in Colombia, Iran, Egypt, Saudi Arabia, and USA which provides a broad international view of public health. He has served in the military reserve hospital for 17 years with extensive training in medical responses to disasters as the chief biochemistry officer of a general hospital, retiring at a Lt. Colonel. He is a distinguished member of several national and international nutrition, immunology, and cancer societies. Dr. Watson's career has involved studying many lifestyle aspects for their uses in health promotion. He has edited over 100 biomedical reference books, particularly in health, and 450 papers and chapters. His teaching and research focuses on alcohol, tobacco and drugs of abuse in heart function and disease in mouse models.
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