Collected Studies from the Bureau of Laboratories, Department of Health, City of New York Volume 3

Collected Studies from the Bureau of Laboratories, Department of Health, City of New York Volume 3

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This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1907 edition. Excerpt: ...linked to the euglobulin fraction as maintained by Pick. Recently observations have been made by Ruediger4 on the relation to the blood proteids of streptolysin, the hemolytic substance produced by the development of streptococci in heated serum. The lysin was precipitated with the globulin by saturation with magnesium sulphate; it was found with both the euglobulin and pseudoglobulin of the fractioned undiluted serum and also in both the insoluble proteid and the filtrate of the dialyzed half saturation ammonium sulphate precipitate. 1 Opie and Barker: Journ. of Exp. Med., ix, p. 207, 1907. 2 Ledingham: Journ. of Hygiene, vii, p. 65, 1907. 8 Brieger (Festschrift fti R. Koch, Jena, 1903) and also one of us (Gibson) have already reported similar experiences. In some as yet unpublished experiments carried on for another purpose by one of us (Gibson) and E. J. Banzhaf of this laboratory, it has been found that if undiluted horse serum be precipitated with half its volume of saturated ammonium sulphate solution and allowed to stand for 18 hours, the euglobulin precipitate may contain over two-thirds of the total serum globulin. Precipitation under the same conditions except that the precipitated mixture is 5 or 10 times the volume of the original serum gives a euglobulin figure only of from a fifth to a third the total globulin. The euglobulin at a dilution of 1 no is noticeably smaller than at 1:5. This fact explains the diminished antitoxic content of reprecipitated or washed euglobulin fraction and makes difficult any hard and fast division into eu-and pseudo-globulins. Ruediger: Journ. of Infect. Diseases, iv, p. 377, 1907. Moll,1 however, has shown that such heating suffices to alter the chemical composition and to change the precipitation...
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Product details

  • Paperback | 52 pages
  • 189 x 246 x 3mm | 109g
  • Miami Fl, United States
  • English
  • black & white illustrations
  • 1236585518
  • 9781236585516