Clinical Nephrotoxins

Clinical Nephrotoxins : Renal Injury from Drugs and Chemicals

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A comprehensive handbook on all aspects of adverse effects by drugs, chemical substances and radiation on the kidneys. The importance of the toxicity of drugs and other substances on the kidneys is increasingly recognized. The book consists of a general part which deals with such themes as clinical relevance and clinical syndromes of nephrotoxicity, renal handling of drugs and pathological expression of nephrotoxicity. The second part includes the specific drugs, for instance the anti-infectious agents, anti-inflammatory drugs, cardiovascular drugs, anti-cancer drugs, etc. The last part deals with prevention consisting of early markers, principles of drug dosage in renal failure and practical dosage.
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Product details

  • Hardback | 528 pages
  • 209.55 x 230 x 31.75mm | 1,338.1g
  • United States
  • English
  • index
  • 0792336119
  • 9780792336112

Table of contents

1. Clinical Relevance; D. Kleinknecht, G.A. Porter. 2. Renal Handling of Drugs and Xenobiotics; M.E. De Broe, F. Roch-Ramel. 3. Immunologically-Mediated Toxin-Induced Renal Diseases; L. Pelletier, P. Druet. 4. Cellular Mechanisms of Nephrotoxicity; E.J. Nouwen, G.A. Porter. 5. Experimental Models. Introduction. B. Specific Drugs. 6. Introduction: Anti-Infectious Agents; J.P. Fillastre. 7. Aminoglycosides and Vancoymycin; G.A. Verpooten, et al. 8. The Renal Toxicity of Beta-Lactam Antibiotics: Mechanisms and Clinical Implications; B.M. Tune, C. Cojocel. 9. Amphotericin B; J. Bernardo, et al. 10. Miscellaneous Drugs with Nephrotoxic Potential; C.A. Vaamonde. 11. Antiviral Agents; J.S. Berns, et al. 12. Introduction: Analgesic Related Renal Injury; M.E. De Broe. 13. Analgesics; M.M. Elseviers, M.E. De Broe. 14. Nonsteroidal Anti-Inflammatory Drugs: Effects on Kidney Function; A. Whelton, A.J. Watson. 15. 5-Aminosalicylic Acid and Chronic Interstitial Nephritis; M.E. De Broe, et al. 16. Nephrotoxicity of Gold Salts, D-Penicillamine, and Allopurinol; S. Ueda. 17. Renal Injury from Angiotensin I Converting Enzyme Inhibitors; P.E. De Jong, L.L. Woods. 18. Diuretics; J.B. Puschett. 19. Anticancer: Cisplatinum/Carboplatinum; R. Safirstein, G. Deray. 20. Introduction: Immunosuppressive Drugs; W.M. Bennett. 21. Immunosuppression: Cyclosporine/Tacrolimus (FK-506); H. Dieperink, et al. 22. OKT3 Nephrotoxicity: From Acute Tubular Necrosis to Hemolytic Uremic Syndrome; D. Abramowicz, et al. 23. Cytokine Associated Renal Dysfunction: Interleukins and Interferons; M.M. Meyer. 24. Contrast Associated Nephropathy: Presentation, Pathophysiology and Management; G.A. Porter, D. Kremer. 25. Introduction: Environmental Nephrotoxins; R.P. Wedeen. 26. Lead Nephropathy; R.P. Wedeen, B.T. Emmerson. 27. Cadmium-Induced Renal Effects in the General Environment; T. Kido, G. Nordberg. 28. Mercury; C.G. Elinder, B.A. Fowler. 29. Role of Environmental/Occupational Exposure to Organic Solvents, Silicon-Containing Compounds and Pesticides in the Development and Progression of Renal Disease; M. Yaqoob, et al. 30. Lithium and the Kidney; D.C. Batlle, E.J. Dorhout-Mees. 31. Renal Disease Associated with Illicit Drug Abuse; C.L. Kunis, G.B. Appel. 32. Renal Toxicity of Anesthetic Agents; P.O. Jarnberg. 33.. Nephrotoxicity of Herbal Remedies and Trace Elements Used as Food Additives; J.L. Vanherweghem. 34. Balkan Nephropathy; L. Djukanovic, et al. C. Prevention. 35. Urinary Biomarkers and Nephrotoxicity; W.F. Finn, G.A. Porter. 36. Principles of Drug Dosing in Renal Failure; M.M. Reidenberg. 37. Practical Dosing; G.A. Verpooten, W.M. Bennett.
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