Clinical Hematology; A Practical Guide to the Examination of the Blood with Reference to Diagnosis

Clinical Hematology; A Practical Guide to the Examination of the Blood with Reference to Diagnosis

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This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1901 edition. Excerpt: ...the hemoglobin estimate and erythrocyte count alone are absolutely uncharacteristic in secondary anemias, for they may range in the individual case from slightly subnormal figures to an extreme degree of oligochromemia and oligocythemia. In a patient studied by von Limbeck,2 for example, at one time the erythrocytes numbered only 306,000 per cubic millimeter, but ultimately perfect recovery ensued and the count rose to 4,280,000. But if averages are used as a basis for conclusions, it becomes evident that the hemoglobin diminution is less marked than in any other blood disease, and that the erythrocyte loss is also less than in any other form of anemia except chlorosis. Data based upon 200 examinations of various types of anemia by the writer give the following results regarding these points: 'Centralbl. f. d. med. Wissensch., 1894, vol. xxxii., p. 785. 2Loc. cit. Examination of the stained specimen shows a variable degree of alteration in the shape, size, and general structure of the cells. In mild cases simple pallor of the erythrocytes, with perhaps a few microcytes and moderately misshapen poikilocytes are the only changes to be observed, erythroblasts, polychromatophiles, and cells with basophilic stroma degeneration being entirely wanting. In severe cases, with excessive oligocythemia, a large proportion of the cells are either under-or over-sized, the latter forms appearing to prevail in relation to the intensity of the anemic process; poikilocytosis and polychromatophilia are sometimes extreme, and evidences of Grawitz's stroma degeneration are found, together with a more or less abundance of nucleated erythrocytes, the majority of which conform to the normoblastic type. In most instances normoblasts only are present, but rarely more

Product details

  • Paperback | 180 pages
  • 189 x 246 x 10mm | 331g
  • Miami Fl, United States
  • English
  • black & white illustrations
  • 1236522737
  • 9781236522733