Chirality in Drug Design and Synthesis
This is a text which deals with the property of left-handed and right-handed structural form in chemicals used in drug design and drug synthesis. The book covers pharmacological, medical, organic chemical and toxicological applications.
- Hardback | 272 pages
- 01 Feb 1991
- Elsevier Science Publishing Co Inc
- Academic Press Inc
- San Diego, United States
Table of contents
Chirality - pharmacological action and drug development, M.Hyneck and J. Dent; therapeutics - problems all along the line, E.J.Ariens; chirality, drug metabolism and action, D.S.Davies; from enzyme mimics to molecular self-assembly processes, J.F.Staddart; modelling of drug-receptor interactions - stereoselectivity of 5-hydroxytryptamine and dopamine receptors in the brain, U.Hacksell et al; molecular basis of the activity of antibiotics of vancomycin group - guides for peptide-peptide binding, D.H.Williams et al; recent developments in the use of enzyme catalyzed reactions in organic synthesis, S.M.Roberts; recent progress in research on the immunosuppressant FK-506, P.Kocienski et al; a practical enantioselective synthesis, I.Lantos and V.Novak; chirality recognition in synthesis, S.G.Davies; sultam-directed asymmetric syntheses of alpha-amino acids, W.Oppolzer.