Chinmedomics

Chinmedomics : The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine

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Description

Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine uses new experimental techniques and research to open doors in drug discovery and development related to traditional Chinese medicine (TCM). This book features a unique approach that combines chemometric analysis with metabolomics studies to illuminate significant changes that have occurred in syndrome states while simultaneously analyzing the efficacy of chemical ingredients in herbal medicines. Chapters provide cutting-edge information on traditional medicine, analytical technology, natural products, metabolomics, bioinformatics and their applications. This book provides a valuable resource for pharmacologists, pharmaceutical scientists, medicinal plant researchers, pharmacognosists and chemists working with TCM and highlights ways to further research and advances in this area in the future.
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Product details

  • Hardback | 408 pages
  • 191 x 235 x 38mm | 788g
  • Academic Press Inc
  • San Diego, United States
  • English
  • Approx. 100 illustrations (100 in full color); Illustrations, unspecified
  • 0128031174
  • 9780128031179

Table of contents

Preface



Origin of Chinmedomics
Methods and protocols of Chinmedomics
Chinmedomics advancing drug discovery and development from Yinchenhao Tang
Chinmedomics approach dissects therapeutic properties of ShenQiWan acting on ShenYangXu syndrome
Metabolic profiling and biomarkers analysis of Jaundice syndrome
Metabolic profiling and biomarkers analysis of GanYuPiXU syndrome
Metabolic profiling and biomarkers of Yinhuang syndrome and evaluation on Yinchensini Tang
Metabolite profiling and biomarkers analysis of Jaundice syndrome related animal model
Metabolomic evaluation of hepatoprotective effect of Yinchenhao Tang and its major bioactive constituents
Metabolomics and proteomics elucidation on therapeutic mechanisms of geniposide
Metabolic profiling and potential biomarkers of ShenYinXu syndrome and therapeutic effect of Liuweidihuang Wan
Metabolic profiling of healthy persons treated with Liuweidihuang Wan
Metabolic profiling and potential biomarkers analysis of ShenYangXu syndrome
Metabolic evaluation of ShenQiWan nourishing ShenYangXu syndrome
Metabolic profiling and biomarkers analysis of XinQiXu syndrome
Active constituents screening based on correlation analysis between marker metabolites and absorbed constituents in Wen-Xin-Formula
Targeted synergism effects of the combined active constituents of Yinchenhao Tang
Metabolic profiling and biomarkers of type 2 diabetes and effective evaluation of Tianqi Jiangtang capsule
Metabolic biomarkers of alcohol liver damage and intervention effect of Yinchenhao Tang
Metabolic profiling and biomarkers analysis of insomnia and intervention effects of Suanzaoren decoction and its related active ingredients
Metabolic biomarkers of nonbacterial prostatitis and treatment evaluation of Phellodendri amurensis cortex and its main components
Metabolic profiling provides a system for understanding of Alzheimer's disease in rats after treatment with Kaixin San
Metabolic profiles delineate the effect of Shengmai San on Alzheimer's disease in rats
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About Xijun Wang

Xijun Wang, PhD, is a Professor of Pharmacology of Traditional Chinese Medicine (TCM) and Vice President at Heilongjiang University of Chinese Medicine in China. Dr. Wang has published more than 150 papers in peer-reviewed journals, received the National Science and Technology Progress Award and National Technological Invention Award and holds 20 patents. His research focuses on serum Pharmacochemistry of Traditional Chinese Medicines. By integrating metabolomics with serum Pharmacochemistry of TCM Dr. Wang has developed and established the theory and research methods of Chinmedomics, whereby the clinical efficacy of TCM formulae can be measured and analyzed.
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