I. Biology of Childhood Leukemia.- 1. Etiological mechanisms in childhood acute lymphoblastic leukemia.- 2. The effects of hemopoietic factors on stem cells in vitro.- 3. Bone marrow stromal cells and hematopoiesis.- 4. Gene transfer investigations of oncogenes activated by chromosomal translocations in human lymphomas and leukemias: BCL2 and C-MYC.- 5. Molecular studies of chromosomal translocations in childhood leukemias.- 6. Molecular analysis of chromosomal abnormalities in childhood acute lymphoblastic leukemia.- 7. Immunological properties of hemotopoietic malignancies in childhood.- 8. Polymerase chain reaction studies on chronic myelogenous leukemias and detection of residual Phi1 clone after bone marrow transplantation.- 9. Lineage-specific classification of childhood leukemia and its clinical implications.- II. Epidemiology of Childhood Leukemia.- 10. The epidemiology of leukemia: Results from the Manchester Children's Tumour Registry.- 11. Contribution of Japan Children's Cancer Registry to medical research and care of childhood leukemia and related conditions.- 12. Long-term survivors of leukemia and late effects: A report from the Registry of Long-Term Survivors of Children's Cancer of Japan.- III. Treatment of Childhood Leukemia.- 13. Therapy of childhood leukemia: Understanding success and failure.- 14. Results and significance of six randomized trials in four consecutive ALL-BFM studies.- 15. Pharmacokinetics of commonly used anti-leukemic agents in children.- 16. Treatment of acute nonlymphoblastic leukemia in the Children's Cancer and Leukemia Study Group.- 17. Treatment of childhood acute lymphoblastic leukemia: The results of the Tokyo Children's Cancer Study Group L84-11 treatment protocol study.- 18. Bone marrow transplantation in children and adolescents with leukemia.- 19. Bone marrow transplantation in children and quality of life in long-term survivors.- 20. Autologous bone marrow transplantation for children with leukemia.- 21. Peripheral blood stem cell autografts in children with acute leukemia and lymphoma.- 22. Varied problems associated with immunocompromised hosts.- IV. The Total Care and the Patient Support System for Children with Leukemia.- 23. Activities of the Children's Cancer Association of Japan.- 24. Candlelighters: Parents and caregivers, friends and allies, working together for life.- 25. Who helps families of children with cancer? Parent and patient support in the U.K..- 26. The Ronald McDonald House program in the United States.- 27. Total care of the child with cancer.- 28. Home care for children with cancer.