Cellular and Molecular Neurobiology
Cellular and Molecular Neurobiology introduces a novel approach to learning and teaching neuroscience. The molecular aspects of ionic channels (voltage and ligand-dependent channels) are clearly explained from a functional view point and with an hypothesis-driven approach firmly based on experiments. Once each channel is explained, it is summed up one-to-one to arrive at the explanation of the basic properties of excitable cells and secretory cells; action potentials, sensory receptor potentials, statistics of transmitter release and synaptic potentials. This building block approach to illustrate the functions of the neuronal plasma membrane also facilitates the explanation of more complex neuronal behaviors. With the aid of over 400 illustrations reconstructed from classical experiments, the chapters are organized to encourage students to ask questions in the face of an observation, to formulate hypotheses, to design experiments to test these hypotheses, and to draw critical conclusions from the results obtained. As a result, it is a book from which students like to learn.
- Paperback | 488 pages
- 162 x 236 x 14mm | 439.99g
- 01 Jan 1996
- Elsevier Science Publishing Co Inc
- Academic Press Inc
- San Diego, United States
- 2 b&w illustrations, 2 colour illustrations, index
Table of contents
General properties of neurons in the nervous tissue: neurons; synapses; glial cells; nervous tissue. Neurons are excitable and secretory cells: the neuronic plasmic membrane; basic properties of excitable cells at rest; the voltage-gated channels of action potentials; neurotransmitter release. Ionotropic receptors in synaptic transmission and sensory transduction: the nicotinic cholinergic receptor nAChR; the GABAA receptor; the iontropic glutamate receptors; mechanoreceptors. Metabotropic receptors in synaptic transmission and sensory transduction: the ABAB receptor; the metabotropic glutamate receptors mGluR; the olfactory receptors. Integration of post-synaptic currents and synaptic plasticity: the integration of post-synaptic currents along the dendritic tree; subliminal voltage-gated currents determine firing pattern; firing patterns of neurons; synaptic plasticity.
About Constance Hammond
Edited by Constance Hammond