Cellular and Molecular Mechanisms of Inflammation: Signal Transduction in Inflammatory Cells, Pt.1 v. 2
A book intended for researchers concerned with immunological responses of inflammatory cells. The localized attachment of circulating leukocytes to the lining of blood vessels has long been recognized as the cellular hallmark of the inflammatory response. This volume reviews our current understanding of the cell surface adhesion molecules that appear to be important determinants of the temporal and spatial patterns, and cellular selectivity, of these leukocyte-vessel interactions. The emphasis is on molecular structure and function as revealed by the most recent studies in this rapidly moving field.
- Hardback | 180 pages
- 01 Jan 1992
- Elsevier Science Publishing Co Inc
- Academic Press Inc
- San Diego, United States
- references, index
Table of contents
Endothelial-leukocyte adhesion molecule-1 (ELAM-1) - a vascular SELECTIN that regulates inflammation, M.P. Bevilacqua; leukocyte interactions mediated by GMP-140, R.P. McEver; leukocyte adhesion molecule-1 (LAM-1) - structure, function, genetics, and evolution, G.S. Kansas; the peripheral lymph node homing receptor - tandem structural and functional domains in a novel class of adhesion molecule, M.H. Siegelman and I.L. Weissman; the Peyer's patch homing receptor - a novel member of the integrin family, M.C.T. Hu B. Holzmann, et al; vascular addressins - tissue selective endothelial cell adhesion molecules for lymphocite homing, E.L. Berg, et al; structure - function relationships of the CD44 class of glycoproteins, W.M. Gallatin, et al; vascular cell adhesion molecule-1, R. Lobb, et al; the role of intercellular adhesion molecule-1 (ICAM-1) in the inflammatory response, R. Rothlein, et al.