Cellular Adhesion in Development and Disease: Volume 112

Cellular Adhesion in Development and Disease: Volume 112

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Cell adhesion is a fundamental determinant of embryonic development and organogenesis. Cellular Adhesion in Development and Disease, volume 112 in Current Topics in Developmental Biology, comprehensively surveys current developments in understanding how adhesion systems affect organismal development. Topics covered include nectins, nectin-like molecules, and afadin in development; cadherin adhesion, signaling, and morphogenesis; endothelial cell junctions; epidermal development and barrier formation; and more.
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Product details

  • Hardback | 536 pages
  • 154.94 x 228.6 x 33.02mm | 929.86g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0124077587
  • 9780124077584

Table of contents

1. How Adhesion forms the early Mammalian Embryo
Melanie D. White and Nicolas Plachta
2. Regulation of Cell Adhesion and Cell Sorting at Embryonic Boundaries
Francois Fagotto
3. Active Tension: The Role of Cadherin Adhesion and Signaling in Generating Junctional Contractility
Rashmi Priya and Alpha S. Yap
4. Integration of Cell-Cell Adhesion and Contractile Actomyosin Activity during Morphogenesis
Katja Roeper
5. Nuclear Signaling from Cadherin Adhesion Complexes
Pierre D. McCrea, Meghan T. Maher and Cara J. Gottardi
6. Nectins and Nectin-Like Molecules in Development and Disease
Kenji Mandai, Yoshiyuki Rikitake, Masahiro Mori and Yoshimi Takai
7. Anchors and Signals: The Diverse Roles of Integrins in Development
Aidan P. Maartens and Nicholas H. Brown
8. Epithelial-Mesenchymal Transitions: From Cell Plasticity to Concept Elasticity
Pierre Savagner
9. Embryonic Cell-Cell Adhesion: A Key Player in Collective Neural Crest Migration
Elias H Barriga and Roberto Mayor
10. VE-Cadherin in Vascular Development: A Coordinator of Cell Signaling and Tissue Morphogenesis
Anne Karine Lagendijk and Benjamin M. Hogan
11. Adhesion in Mammary Development: Novel Roles for E-Cadherin in Individual and Collective Cell Migration
Eliah R. Shamir and Andrew J. Ewald
12. Cell Adhesion in Epidermal Development and Barrier Formation
Kaelyn D. Sumigray and Terry Lechler
13. Cadherin-Based Trans-Synaptic Networks in Establishing and Modifying Neural Connectivity
Lauren G. Friedman, Deanna L. Benson and George W. Huntley
14. Cell-Cell Interactions Driving Kidney Morphogenesis
Alexander N. Combes, Jamie Davies and Melissa Little
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About Alpha Yap

Alpha Yap is a Professor and Head of the Division of Molecular Cell Biology at the Institute for Molecular Bioscience, The University of Queensland. After training in Internal Medicine, Endocrinology and Cell Physiology, he undertook post-doctoral research with Barry Gumbiner at Memorial Sloan-Kettering Cancer Center before returning to Australia to establish his independent research group. His laboratory studies the cellular mechanisms responsible for cadherin-dependent morphogenesis, notably the mechanisms and principles that coordinate cadherin adhesion with the cytoskeleton. He was Chair of the 2011 Gordon Research Conference on Cell Contact & Adhesion and will chair the 2016 GRC on Signaling by Adhesion Receptors. He currently serves on the editorial boards of several journals, amongst them Molecular Biology of the Cell, Developmental Cell and Current Biology. He is the recipient of the 2013 President's Medal of the Australia and New Zealand Society for Cell and Developmental Biology.
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