Catastrophic Brain Injury

Catastrophic Brain Injury

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Description

This book integrates clinical and research findings on catastrophic brain injury. The clinical chapters address the definition, epidemiology, pathophysiology, and outcomes of the most severe closed head injuries that typically result in death or neurobehavioural sequelae. The chapters on experimental research include reviews of recent advances in characterizing neurochemical interactions contributing to secondary brain injury. A summary chapter synthesizes the clinical and experimental material, provides an update concerning ongoing clinical trials, and offers a perspective on future directions of research to mitigate the consequences of severe head injury.show more

Product details

  • Hardback | 278 pages
  • 164.6 x 243.8 x 20.6mm | 641.97g
  • Oxford University Press Inc
  • New York, United States
  • English
  • New.
  • 1 colour plate, line figures, tables
  • 0195085337
  • 9780195085334

Back cover copy

This book provides a superb integration of clinical and research findings on catastrophic brain injury. The clinical chapters address the definition, epidemiology, pathophysiology, and outcome of the most severe closed head injuries that typically result in death or devastating neurobehavioral sequelae. They cover cerebral metabolism following catastrophic brain injury, medical management, pharmacologic treatment for survivors, the impact on the family, and legal and ethical issues. The chapters on experimental research include reviews of recent advances in characterizing neurochemical interactions contributing to secondary brain injury and of experimental studies of the effects of neural transplantation on cognitive performance in animals. A summary chapter synthesizes the clinical and experimental material, provides an update concerning ongoing clinical trials to evaluate the efficacy of drugs and hypothermia in the treatment of acute severe head injury, and offers a perspective on future directions of research to mitigate the consequences of severe head injury.show more

Table of contents

1. Clinical and Pathological Features of Vegetative Survival ; 2. Epidemiology of Catastrophic Brain Injury ; 3. Vegetative State after Head Injury: Findings from the Traumatic Coma Data Bank ; 4. Cerebral Function Following Catastrophic Brain Injury: Relevance of Single Photon Emission Computerized Tomography ; 5. Medical Problems in the Management of Catastrophic Brain Injury ; 6. Pharmacologic Treatment for Survivors of Severe Brain Injury ; 7. Cognitive and Linguistic Outcome ; 8. Moral, Ethical and Legal Issues Raised by Catastrophic Brain Injury ; 9. Family Perceptions and Family Reactions: Reconsidering "Denial" ; 10. Neurochemical Changes in Traumatic Brain Injury ; 11. Tissue Transplantation ; 12. Advances in Experimental Research and Clinical Intervention for Catastrophic Brain Injury: The Early 21st Centuryshow more

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