Cardiovascular Aging : Clinical Applications of Cellular and Molecular Mechanisms
Cardiovascular Aging: Linking Cellular and Molecular Mechanisms is a first-of-its-kind resource linking age-related cardiovascular disease to its molecular pathomechanism. With full coverage of the essential cellular and molecular mechanisms of ageing, this valuable resource will provide the important connection between research and clinical application, highlighting paths in translational science and pointing to future interventions.
- Hardback | 384 pages
- 216 x 276mm
- 01 Nov 2018
- Elsevier Science Publishing Co Inc
- Academic Press Inc
- San Diego, United States
- Approx. 150 illustrations (150 in full color); Illustrations, unspecified
About Iokim Spyridopoulos
Dr. Iokim Spyridopoulos, Professor of Cardiology, Chair of Cardiovascular Gerontology (Newcastle University) and Honorary Consultant Interventional Cardiologist (Newcastle Hospitals NHS Trust); Newcastle Upon Tyne, UK . Professor and practicing interventional cardiologist. Active in grant review, journal review, and contributor to over 30 publications. . Memberships: Royal College of Physicians; German Cardiac Society; Fellow of the European Society of Cardiology (FESC) . Active member of Research Gate, (Facebook of Research) with a quickly growing community of scientists. . Honorary Consultant Interventional Cardiologist, Freeman Hospital, . Newcastle upon Tyne Hospitals, NHS Foundation Trust Key Publications: Spyridopoulos I, Hoffmann J, Aicher A, Br mmendorf TH, Doerr HW, Zeiher AM, Dimmeler S. Accelerated telomere shortening in leukocyte subpopulations of patients with coronary heart disease: role of cytomegalovirus seropositivity. Circulation. 2009;120:1364-72 Spyridopoulos I, Erben Y, Brummendorf TH, Haendeler J, Dietz K, Seeger F, Kissel CK, Martin H, Hoffmann J, Assmus B, Zeiher AM, Dimmeler S. Telomere gap between granulocytes and lymphocytes is a determinant for hematopoetic progenitor cell impairment in patients with previous myocardial infarction. Arterioscler Thromb Vasc Biol. 2008;28:968-974. Spyridopoulos I, Fichtlscherer S, Popp R, Toennes SW, Fisslthaler B, Trepels T, Zernecke A, Liehn EA, Weber C, Zeiher AM, Dimmeler S, Haendeler J. Caffeine Enhances Endothelial Repair by an AMPK-Dependent Mechanism. Arterioscler Thromb Vasc Biol. 2008;28:1967-1974. Spyridopoulos I, Dimmeler S. Can telomere length predict cardiovascular risk? Lancet. 2007;369:81-82. Spyridopoulos I, Haendeler J, Urbich C, Brummendorf TH, Oh H, Schneider MD, Zeiher AM, Dimmeler S. Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells. Circulation. 2004;110:3136-3142.