Brain Development and Epilepsy

Brain Development and Epilepsy

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This is an integrated view of the special features of epileptic syndromes in the immature brain. The immature brain is quite different from its adult counterpart and understanding of normal and pathological functions in the immature central nervous system (CNS) require a special appreciation of developmentally unique mechanisms. This is the first time that basic developmental neurobiological insights and clinical neurological understanding relevant to the epilepsies are presented more

Product details

  • Hardback | 350 pages
  • 152.4 x 238.8 x 27.9mm | 771.12g
  • Oxford University Press Inc
  • New York, United States
  • English
  • halftones, line figures, tables
  • 0195078462
  • 9780195078466

Table of contents

Introduction; 1. A clinician's look at the developmental neurobiology of epilepsy; 2. Partial (focal) seizures in developing brain; 3. Absence seizures in developing brain; 4. Developmental neuropathology and childhood epilepsies; 5. Neuronal identity, neuronal migration and epileptic disorders of the cerebral cortex; 6. Regulation of excitability in developing neurons; 7. Candidate genes in the childhood epilepsies: Molecular biology of channels and receptors; 8. Synaptogenesis and epileptogenesis in developing neural networks; 9. Plasticity and repair in the immature central nervous system; 10. Seizure-induced changes in the immature brain; 11. Age-specific antiepileptic drug treatment and development of new age-specific, antiepileptic drugs; Epilogueshow more