Biology of Serpins: Volume 499

Biology of Serpins: Volume 499

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Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. This volume of Methods in Ezymology is split into 2 parts and comprehensively covers the subject.
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Product details

  • Hardback | 456 pages
  • 152.4 x 231.14 x 27.94mm | 861.82g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0123864712
  • 9780123864710

Table of contents

Analysis of Serpin Secretion, Misfolding and Surveilance in the Endoplasmic Reticulum
Shujuan Pan, Michael J. Iannotti and Richard N. Sifers

Serpin-Enzyme Receptors: Ldl Receptor Related Protein 1
Dudley K. Strickland, Selen Catania Muratoglu and Toni M. Antalis

The Role of Autophagy in Alpha-1-Antitrypsin Deficiency
Tunda Hidvegi, Amitava Mukherjee, Michael Ewing, Carolyn Kemp and David H. Perlmutter

Serpins and the Complement System
Laszlo Beinrohr, Thomas A. Murray-Rust, Leanne Dyksterhuis, Peter Zavodszky, Peter Gal, Robert N. Pike and Lakshmi C. Wijeyewickrema

Use of Mouse Models to Study Plasminogen Activator Inhibitor-1
Paul J. Declerck, Ann Gils and Bart De Taeye

Plasminogen Activator Inhibitor Type 2: Still An Enigmatic Serpin But A Model For Gene Regulation
Robert L. Medcalf

The Serpinb1 Knock-Out Mouse: A Model For Studying Neutrophil Protease Regulation in Homeostasis and Inflammation
Charaf Benarafa

Investigating Maspin in Breast Cancer Progression Using Mouse Models
Michael P. Endsley and Ming Zhang

Hsp47as A Collagen-Specific Molecular Chaperone
Yoshihito Ishida and Kazuhiro Nagata

Assays for the Antiangiogenic and Neurotrophic Serpin Pigment Epithelium-Derived Factor
S. Patricia Becerra, Susan E. Crawford and Preeti Subramanian

The Drosophila Serpins: Multiple Functions in Immunity and Morphogenesis
Jean Marc Reichhart, David Gubb and Vincent Leclerc

Modelling Serpin Conformational Diseases in Drosophila Melanogaster
Thomas R. Jahn, Elke Malzer, John Roote, Anastasia Vishnivetskaya, Sara Imarisio, Maria Giannakou, Karin Panser, Stefan Marciniak, Damian C. Crowther

Using Caenorhabditis Elegans to Study Serpinopathies
Olivia S. Long, Sager J. Gosai, Joon Hyeok Kwak, Dale E. King, David H. Perlmutter, Gary A. Silverman and Stephen C. Pak

Using c. Elegans to Identify the Protease Targets of Serpins In Vivo.
Sangeeta R. Bhatia, Mark T. Miedel, Cavita K. Chotoo, Nathan J. Graf, Brian L. Hood, Thomas P. Conrads, Gary A. Silverman and Cliff J. Luke

Viral Serpin Therapeutics: From Concept to Clinic
Hao Chen, MD, PhD, Donghang Zheng, MD, PhD, Jennifer Davids, BA, Mee Yong Bartee, PhD, Erbin Dai, MD, Liying Liu, MD, Lyubomir Petrov, MD, PhD, Colin Macaulay, PhD, Robert Thoburn, MD, Eric Sobel, MD, PhD, Richard Moyer, PhD, Grant McFadden, PhD, Alexandra Lucas, MD, FRCP(C)

Human Scca Serpins Inhibit Staphylococcal Cysteine Proteases by Forming Classic "Serpin-Like" Covalent Complexes
Tomasz Kantyka and Jan Potempa

Plants and the Study of Serpin Biology

Thomas H. Roberts, Joon-Woo Ahn, Nardy Lampl and Robert Fluhr
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