Biological Oxidation Systems: v. 1
The first of two volumes containing the proceedings of an October 1989 conference in Bangalore, India, sponsored by the US National Science Foundation. The theme is the molecular mechanisms by which free oxygen and its reduction products, like superoxide and peroxides, react in biological systems. In addition to an overview of the subject, 32 papers discuss cytochrome P-450 catalyzed reactions, oxidases and oxygenases containing a flavin/pteridine, copper-containing oxidases and oxygenases, nonheme iron-containing and other oxygenases, and peroxidases in cell protection and metabolism. Annotation copyright Book News, Inc. Portland, Or.
- Hardback | 546 pages
- 150 x 225 x 31.75mm | 906g
- 01 Oct 1990
- Elsevier Science Publishing Co Inc
- Academic Press Inc
- San Diego, United States
Table of contents
Part 1 Overview - mechanisms of biological oxidations: mechanisms of biological oxidation reactions involving oxygen and reduced oxygen derivatives, G.A.Hamilton. Part 2 Cytochrome P-450-catalyzed reactions: the cytochrome P-450 superfamily - impact on biology and medicine, R.W.Estabrook, et al; transcriptual regulation of cytochrome P-450b/e gene expression in rat liver, G.Padmanaban, et al; oxidation reactions catalyzed by cytochrome, F.P.Guengerich; cellular responses to oxidative stress, D.W.Nebert, et al; abberations in cytochrome P-450 and mixed function oxidase system, B.L.Tekwani and O.P.Shukla; preferential induction of biological oxidation systems in alkaloid metabolism of plant tissue cultures subjected to fungal elicitation, S.D.Cline, et al; (+)-pulegone-mediated hepatotoxicity in rat, role of microsomal cytochrome P-450, K.M.Madyaastha and B.Moorthy; cytochrome P-450-catalyzed reactions in brain, P.K.Seth, et al; microsomal cytochrome P-450 mediated N-oxygenation of amino azaheterocyccles, J.W.Gorrod and S.P.Lam; presence of phenobarbital and 3-methylcholanthrene inducible forme of cytochrome P-450 in rat brain, V.Ravindranath and H.K.Anandatheerthanvarada; reciprocal posttranslational regulations of chick kidney mitochondrial 1a- and 24R-hydroxylase of 25-hydroxyvitamin D3, J.G.Ghazarian, et al; cytoprotective mechanisms that offset the potential augmentation of phenobarabital-induced O2 generation during quinone recycling, W.S.Utley, and H.M.Mehendale. Part 3 Oxidases and oxygenases containing a flavin/pteridine: studies on the mechanism of the uncoupled reaction catalyzed by rat liver phenylalanine, S.Kaufman; why is the co-factor for the tetrahydrobiopterin-dependent monooxygenases not a dihydroflavin?, J.E.Ayling and S.W.Bailey; biochemical aspects of molybdopterin, K.V.Rajagoplan and J.L.Johnson; the kinetics and regulation of aromatic amino acid hydroxylases - the effect of cofactor structure, S.W.Bailey, et al; the mechanism of oxygen activation by flavoprotein monooxygenase, M.G.Taylor and V.Massey. Part 4 Copper-containing oxidases and oxygenases: copper proteins - a review of the different classes of copper proteins and an in-depth investigation of the active copper sites in dopamine b-hydroxylase, J.J.Villafranca and P.R.Desai; structure function studies of dopamine b-hydroxylase, J.P.Klinman, et al; novel oxidation chemistry of catecholamine derivatives and related compounds, M.Sugumaran. Part 5 Nonheme iron-containing and other oxygenases: methane monooxygenase - a novel biological catalyst for hydrocarbon oxidations, B.G.Fox and J.D.Lipscomb; ozone-induced alterations in quantity and activity of rubisco - implications for foliar senescence, E.J.Pell, et al...........Part contents.