Preface; V.A. Saks, et al. Introduction: What Do we Not Know of Cellular Bioenergetics? A General View on the State of Art; V.A. Saks, et al. Part I: Bioenergetics of Mitochondria: in Vitro and in Vivo Studies. 1. Top-Down Elasticity Analysis and Its Application to Energy Metabolism in Isolated Mitochondria and Intact Cells; M.D. Brand. 2. A Model of O2-Generation in the Complex III of the Electron Transport Chain; O.V. Demin, et al. 3. Quantitative Analysis of Some Mechanisms Affecting the Yield of Oxidative Phosphorylation: Dependence Upon Both Fluxes and Forces; M. Rigoulet, et al. 4. Oxidative Phosphorylation in Intact Hepatocytes: Quantitative Characterization of the Mechanisms of Change in Efficiency and Cellular Consequences; X. Leverve, et al. 5. Yeast Mitochondrial Metabolism: From in vitro to in situ Quantitative Study; N. Averet, et al. 6. Permeabilized Cell and Skinned Fiber Techniques in Studies of Mitochondrial Function in vivo; V.A. Saks, et al. 7. Cytoskeleton and Mitochondrial Morphology and Function; L. Rappaport, J.L. Samuel. 8. Energetics of Swelling in Isolated Hepatocytes: A Comprehensive Study; A. Devin, et al. Part II: Energy Transfer Networks: Molecular Physiology of Kinases, Lessons from Transgenic Mice, Mathematical Theories. 9. Functional Aspects of the X-Ray Structure of Mitochondrial Creatine Kinase: A Molecular Physiology Approach; U. Schlattner, et al. 10. Oligomeric State and Membrane Binding Behaviour of Creatine Kinase Isoenzymes: Implications for Cellular Function andMitochondrial Structure; O. Stachowiak, et al. 11. Molecular Characterization of the Creatine Kinases: and Some Historical Perspectives; Wenning Qin, et al. 12. Adenylate Kinase: Kinetic Behavior in Intact Cells Indicates it is Integral to Multiple Cellular Processes; P. Dzeja, et al. 13. Cytoarchitectural and Metabolic Adaptations in Muscles with Mitochondrial and Cytosolic Creatine Kinase Deficiencies; K. Steeghs, et al. 14. In situ Measurements of Creatine Kinase Flux by NMR. The Lessons from Bioengineered Mice; K. Nicolay, et al. 15. Mathematical Model of Compartmentalized Energy Transfer: Its Use for Analysis and Interpretation of 31P-NMR Studies of Isolated Heart of Creatine Kinase Deficient Mice; M.K. Aliev, et al. 16. Functional Coupling of Creatine Kinases in Muscles: Species and Tissue Specificity; R. Ventura-Clapier, et al. 17. Theoretical Modelling of Some Spatial and Temporal Aspects of the Mitochondrion/Creatine Kinase/Myofibril System in Muscle; G.J. Kemp, et al. 18. Quantitative Studies of Enzyme-Substrate Compartmentation, Functional Coupling and Metabolic Channeling in Muscle Cells; V. Saks, et al. Part III: Metabolic Signalling and Calcium: Regulation of Mitochondrial Oxidative Phosphorylation in vivo. 19. Subtleties in Control by Metabolic Channeling and Enzyme Organization; B.N. Kholodenko. 20. The Dynamic Regulation of Myocardial Oxidative Phosphorylation: Analysis of the Response Time of Oxygen Consumption; J.H.G.M. van Beek, et al. 21. Is it Possible to Predict Any Properties of Oxidative Phosphorylation in a Theoretical Way? B. Korzeniewski.