Bioactive Compounds from Natural Sources

Bioactive Compounds from Natural Sources : Isolation, Characterization and Biological Properties

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Description

Interest in obtaining biologically active compounds from natural sources has recently spiked due to their low toxicity, complete biodegradability, availability from renewable sources, and in most cases, low cost. Taking an interdisciplinary approach, Bioactive Compounds from Natural Sources: Isolation, Characterization, and Biological Properties covers general methods and main topics in the research field of bioactive natural products. The book describes general screening methods, modern HPLC hyphenated techniques, and NMR methods in the structural elucidation of compounds and devotes individual chapters to specific topics of research. Surveys on compounds displaying important pharmacological activities are presented in chapters devoted to Mexican medicinal plants, anti-tumor drugs of natural origin, cancer chemopreventive flavonoids, and metabolites displaying anti-HIV, antioxidative, antimalarial, and anti-inflammatory activity. The final chapters are devoted to representative examples of research into marine metabolites: immunomodulating marine glycolipids and surveys of bioactive compounds from marine opisthobranchs and Japanese soft corals. With its focus on modern approaches to the isolation of biologically active natural products, this book encourages interdisciplinary work among chemists, pharmacologists, biologists, botanists, and agronomists with an interest in bioactive natural products.show more

Product details

  • Hardback | 693 pages
  • 177.8 x 256.5 x 43.2mm | 1,338.11g
  • Taylor & Francis Ltd
  • London, United Kingdom
  • English
  • 1, black & white illustrations
  • 0748408908
  • 9780748408900

Table of contents

Biological Screening Methods in the Search for Pharmacologically Active Natural Products; A.J. Vlietinck and S. Apers Applications of Liquid Chromatography/UV/MS and Liquid Chromatography/NMR for the On-line Identification of Plant Metabolites; K. Hostettmann and J.L. Wolfender Applications of Modern NMR Techniques in the Structural Elucidation of Bioactive Natural Products; P. Neri and C. Tringali Bioactive Secondary Metabolites From Selected Mexican Medicinal Plants: Recent Progress; R. Mata, J.F. Rivero-Cruz and D. Chavez Flavonoids as Cancer Chemopreventive Agents; L.C. Chang and A.D. Kinghorn Anti-tumor Drugs from the Secondary Metabolites of Higher Plants; Y.H. Kuo and M.L. King Bioactive Taxoid Production from Natural Sources; M. Jaziri and M. Vanhaelen Anti-HIV Aromatic Compounds from Higher Plants; F. De Simone, R. Aquino, N. De Tommasi, N. Mahmood, S. Piacente and C. Pizza Antioxidative Plant Constituents; H. Haraguchi Antimalarial Natural Products; S. Brogger Christensen and A. Kharazmi Search for Natural Products with Effect on Cyclooxygenase-2; P. Perera, T. Ringbom, U. Huss, M. Vasange and L Bohlin Phytotoxins From Fungi Pathogenic for Agrarian, Forestall and Weedy Plants; A. Evidente and A. Motta Limonoids From Meliaceae and their Biological Activities; M. Nakatani Glycolipids with Immunomodulating Activity From Marine Sponges; V. Constantino, E. Fattorusso and A. Mangoni Metabolites of Marine Opistobranchs: Chemistry and Biological Activity; G. Cimino, M.L. Ciavatta, A. Fontana and M. Gavagnin Bioactive Diterpenoids From Japanese Soft Corals; K. Yamada and R.. Higuchishow more