The Behavioral Neurology of White Matter

The Behavioral Neurology of White Matter

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This text examines the role of the brain's white matter in the organization of human mental function. The white matter is discussed as an important complement to cortical and subcortical gray matter in the distributed neural networks that subserve all aspects of cognition and emotion. The book is founded on the study of patients with white matter disorders, and considers white matter dementia and other neobehavioural syndromes in developing a behavioural neurology of white matter.show more

Product details

  • Hardback | 298 pages
  • 157.5 x 236.2 x 33mm | 635.04g
  • Oxford University Press Inc
  • New York, United States
  • English
  • numerous halftones
  • 019513561X
  • 9780195135619

Review quote

." . . the only book of its kind . . . the white matter should be ignored no more! Indeed, Dr. Filley's book has done (and will do) more to promote the white matter than any other article, treatise, or tome to date." --The Clinical Neuropsychologist"Clinicians and neurobiologists from many disciplines will find this to be a useful volume. The description of the diseases themselves is a worthwhile contribution, and creating the context for these disorders in an understanding of the neurobiology of white matter provides a unique new perspective on old diseases. Those who make themselves students of Dr. Filley's extensive knowledge of white matter and white matter disorders by reading this book will find themselves richly rewarded for their efforts."-- Jeffrey L. Cummings, M.D., Director, UCLA Alzheimers Disease Center, The Augustus S. RoseProfessor of Neurology, and Professor of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine (from the foreword)"The exqui ." . . the only book of its kind . . . the white matter should be ignored no more! Indeed, Dr. Filley's book has done (and will do) more to promote the white matter than any other article, treatise, or tome to date." --The Clinical Neuropsychologist "Clinicians and neurobiologists from many disciplines will find this to be a useful volume. The description of the diseases themselves is a worthwhile contribution, and creating the context for these disorders in an understanding of the neurobiology of white matter provides a unique new perspective on old diseases. Those who make themselves students of Dr. Filley's extensive knowledge of white matter and white matter disorders by reading this book will find themselves richly rewarded for their efforts."-- Jeffrey L. Cummings, M.D., Director, UCLA Alzheimers Disease Center, The Augustus S. Rose Professor of Neurology, and Professor of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine (from the foreword) "The exquisitely written book provides a much-needed overview of white matter and its behavioral correlates...an excellent summary...written in such a way as to be useful for experienced adult and pediatric neurologists, neuropsychiatrists, and neuropsychologists. Furthermore, students of neurosciences and neuropsychology would certainly from the study of this text." --Applied Neuropsychology "In this soon-to-be landmark textbook, Dr. Filley provides an integrative framework for understanding the unique role of white matter in influencing the distributed neural networks that govern higher mental functions. The Behavioral Neurology of White Matter is essential reading for all who seek knowledge of how the brainimpacts behavior."-- Stephen M. Rao, Ph.D., Professor Neurology, Medical College of Wisconsin "Not a week goes by in my clinical practice without having to address the nature of white matter abnormalities seen on a patients MRI scan...Dr. Filley's book represents the most comprehensive state-of-the-art approach to this emerging and increasingly important topic. I will keep it by my desk for regular consultation."-- Bruce H. Price, M.D., Chief, Department of Neurology, McLean Hospital, and Assistant Professor of Neurology, Harvard Medical School "This exquisitely written book provides a much-needed overview of white matter and its behavioral correlates . . . an excellent summary . . ." "This exquisitely written book provides a much-needed overview of white matter and its behavioral correlates . . . an excellent summary . . ." --Ipplied Neuropsycholgoy "[There is] an impressive amount of evidence-- clinical, experimental, and radiological--to compel a realization that, in some instances, mental functioning and behavior may depend as much on the integrity of cerebral white matter as on gray. This important work will help neurologists in particular to develop familiarity with clinical white matter disorders that cause higher cerebral dysfunction."--Stuart A. Schneck, M.D., Professor Emeritus of Neurology, University of Colorado School of Medicine ," . . the only book of its kind . . . the white matter should be ignored no more! Indeed, Dr. Filley's book has done (and will do) more to promote the white matter than any other article, treatise, or tome to date." --The Clinical Neuropsychologist "Clinicians and neurobiologists from many disciplines will find this to be a useful volume. The description of the diseases themselves is a worthwhile contribution, and creating the context for these disorders in an understanding of the neurobiology of white matter provides a unique new perspective on old diseases. Those who make themselves students of Dr. Filley's extensive knowledge of white matter and white matter disorders by reading this book will find themselves richly rewarded for their efforts."-- Jeffrey L. Cummings, M.D., Director, UCLA Alzheimers Disease Center, The Augustus S. Rose Professor of Neurology, and Professor of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine (from the foreword) "The exquisitely written book provides a much-needed overview of white matter and its behavioral correlates...an excellent summary...written in such a way as to be useful for experienced adult and pediatric neurologists, neuropsychiatrists, and neuropsychologists. Furthermore, students of neurosciences and neuropsychology would certainly from the study of this text." --Applied Neuropsychology "In this soon-to-be landmark textbook, Dr. Filley provides an integrative framework for understanding the unique role of white matter in influencing the distributed neural networks that govern higher mental functions. The Behavioral Neurology of White Matter is essential readingfor all who seek knowledge of how the brain impacts behavior."-- Stephen M. Rao, Ph.D., Professor Neurology, Medical College of Wisconsin "Not a week goes by in my clinical practice without having to address the nature of white matter abnormalities seen on a patients MRI scan...Dr. Filley's book represents the most comprehensive state-of-the-art approach to this emerging and increasingly important topic. I will keep it by my desk for regular consultation."-- Bruce H. Price, M.D., Chief, Department of Neurology, McLean Hospital, and Assistant Professor of Neurology, Harvard Medical School "This exquisitely written book provides a much-needed overview of white matter and its behavioral correlates . . . an excellent summary . . ." "This exquisitely written book provides a much-needed overview of white matter and its behavioral correlates . . . an excellent summary . . ." --Ipplied Neuropsycholgoy "[There is] an impressive amount of evidence-- clinical, experimental, and radiological--to compel a realization that, in some instances, mental functioning and behavior may depend as much on the integrity of cerebral white matter as on gray. This important work will help neurologists in particular to develop familiarity with clinical white matter disorders that cause higher cerebral dysfunction."--Stuart A. Schneck, M.D., Professor Emeritus of Neurology, University of Colorado School of Medicine ." . . the only book of its kind . . . the white matter should be ignored no more! Indeed, Dr. Filley's book has done (and will do) more to promote the white matter than any other article, treatise, or tome to date." --The Clinical Neuropsychologist"Clinicians and neurobiologists from many disciplines will find this to be a useful volume. The description of the diseases themselves is a worthwhile contribution, and creating the context for these disorders in an understanding of the neurobiology of white matter provides a unique new perspectiveon old diseases. Those who make themselves students of Dr. Filley's extensive knowledge of white matter and white matter disorders by reading this book will find themselves richly rewarded for their efforts."-- Jeffrey L. Cummings, M.D., Director, UCLA Alzheimers Disease Center, The Augustus S. RoseProfessor of Neurology, and Professor of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine (from the foreword)"The exquisitely written book provides a much-needed overview of white matter and its behavioral correlates...an excellent summary...written in such a way as to be useful for experienced adult and pediatric neurologists, neuropsychiatrists, and neuropsychologists. Furthermore, students ofneurosciences and neuropsychology would certainly from the study of this text." --Applied Neuropsychology"In this soon-to-be landmark textbook, Dr. Filley provides an integrative framework for understanding the unique role of white matter in influencing the distributed neural networks that govern higher mental functions. The Behavioral Neurology of White Matter is essential reading for all who seekknowledge of how thebrain impacts behavior."-- Stephen M. Rao, Ph.D., Professor Neurology, Medical College of Wisconsin"Not a week goes by in my clinical practice without having to address the nature of white matter abnormalities seen on a patients MRI scan...Dr. Filley's book represents the most comprehensive state-of-the-art approach to this emerging and increasingly important topic. I will keep it by my desk forregular consultation."-- Bruce H. Price, M.D., Chief, Department of Neurology, McLean Hospital, and Assistant Professor of Neurology, Harvard Medical School"This exquisitely written book provides a much-needed overview of white matter and its behavioral correlates . . . an excellent summary . . .""This exquisitely written book provides a much-needed overview of white matter and its behavioral correlates . . . an excellent summary . . ." --Ipplied Neuropsycholgoy"[There is] an impressive amount of evidence-- clinical, experimental, and radiological--to compel a realization that, in some instances, mental functioning and behavior may depend as much on the integrity of cerebral white matter as on gray. This important work will help neurologists in particularto develop familiarity with clinical white matter disorders that cause higher cerebral dysfunction."--Stuart A. Schneck, M.D., Professor Emeritus of Neurology, University of Colorado School of Medicineshow more

Table of contents

PART 1: THE BRAIN, THE MIND AND WHITE MATTER; 1. The Neurologic Background; 2. White Matter Structure and Function; 3. Development and Aging; 4. Neuroimaging; PART 2: DISORDERS OF WHITE MATTER; 5. Genetic Disorders; 6. Demyelinative Diseases; 7. Infectious Diseases; 8. Inflammatory Diseases; 9. Toxic Leukoencephalopathies; 10. Metabolic Disorders; 11. Vascular Diseases; 12. Traumatic Disorders; 13. Neoplasms; 14. Hydrocephalus; PART 3: WHITE MATTER AND HIGHER FUNCTION; 15. Cognitive Disfunction and Dementia; 16. Focal Neurobehavioral Syndromes; 17. Neuropsychiatric Syndromes; 18. The Behavioral Neurology of White Matter; INDEXshow more

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