Azolides in Organic Synthesis and Biochemistry

Azolides in Organic Synthesis and Biochemistry

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In the late fifties and early sixties H. A. Staab discovered N,N carbonyl diimidazole (CDI), its analogues, and the family of azolides derived from them. Soon these compounds became widely appreciated as synthetic building blocks of unsurpassed diversity. The spectrum of substances, that can be obtained via mild acylation with azolides includes esters, amides, ketones, aldehydes, as well as heterocycles, peptides, glycosides, and nucleotides. Now, H. A. Staab, the father of these useful compounds, together with his coauthors H. Bauer and K. M. Schneider, has gathered their preparation, properties, and manifold applications in a comprehensive and topical overview. Are you in the field of synthesis of natural products, biomolecules, heterocycles, or other complicated organic compounds? Then, your first glance might well be into Staab. This handbook should always be within reach of your desk or lab more

Product details

  • Other digital | 320 pages
  • 1 x 1 x 1mm
  • Wiley-VCH Verlag GmbH
  • Weinheim, Germany
  • 3527600833
  • 9783527600830

Table of contents

Reactivity of Azolides Preparation and Properties of Azolides Syntheses of Carboxylic and Carbonic Esters Syntheses of Amides and Analogous Compounds with NH-CO-Functions Syntheses of Peptides Modification and Immobilization of Proteins (Enzymes) Syntheses of Heterocycles Syntheses of Isocyanates, Isothiocyanates, Aminoisocyanates, Aminoisothiocyanates and N-Sulfinylamines Reactions of Imino Analogues of Azolides Syntheses of Sulfonates, Sulfinates, Sulfonamides, Sulfoxylates, Sulfones, Sulfoxides, Sulfites, Sulfates and Sulfanes Reaction of Phosphines with N, N'-Carbonyldiimidazole (CDI) Phosphorylation and Syntheses of Nucleotides Syntheses of Acid Anhydrides and Acyl Chlorides C-Acylations and other Element-Acylations Syntheses of Aldehydes Deoxygenation of Alcohols and C-C Coupling Reactions Syntheses of Glycosides and Ethers Intramolecular Dehydration The Acyl Groups of Azolides as Protecting Groups Azole Transfer Syntheses of Halogenides/Pseudohalogenides and Aromatic Amines Reactions with Vinylogous Azolides Photochemical Reactions Special Practical Applications and Analytical Methodsshow more

Author information

Staab, H. A.: Thoretische Organische Chemie. 4. Auflage 1975, DM 64.00, ca. 2000 copies soldshow more