The Autoimmune Diseases

The Autoimmune Diseases

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Since the First Edition of The Autoimmune Diseases was published in 1985, interest as well as knowledge about autoimmune diseases has greatly increased. This edition incorporates new material and combines the basic aspects of autoimmunity with discussion of specific autoimmune diseases in humans. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels. In addition to a comprehensive discussion of various autoimmune diseases and organ systems, the editors also cover the role of autoimmunity in cancer, AIDS, and aging.
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Product details

  • Hardback | 700 pages
  • 214 x 278 x 46mm | 1,900.57g
  • Academic Press Inc
  • San Diego, United States
  • English
  • Revised
  • 3rd Revised edition
  • b&w illustrations, references, index
  • 0125969236
  • 9780125969239

About Noel R. Rose

Noel R. Rose. Residence: Baltimore, Maryland. Affiliation: John Hopkins University School of Hygiene and Public Health, Baltimore, Maryland
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Table of contents

Four decades of self and non-self - reflection on autoimmunity and tolerance, G.J.V. Nossal; basis and mechanisms of self-tolerance, A. Basten; animal models of autoimmunity - spontaneous and induced, P.E. Bigazzi; transgenic models of peripheral t-cell self-tolerance and autoimmunity, J.F.A.P. Miller; genetic influences - MHC, G. Nepom and W.W. Kwok; non-MHC genetic contributions to autoimmune diseases, B.L. Kotzin et al; environmental determinants of autoimmune disease, A. Rosen and L. Casciola-Rosen; infection and autoimmune disease, L.C. Harrison and G.J. McColl; antigenic determinants involved in induction and propagation of autoimmunity, K.D. Moudgil and E.E. Sercarz; antigen receptors, E. Heber-Katz; molecular mimicry, R.S. Fujinami; t-helper cell subsets (TH1, TH2) and cytokines in autoimmunity, S. Romagnani; apoptosis, autoantigens and autoimmunity, C.A. Casiano and E.M. Tan; co-stimulation and the regulation of autoimmunity, K.J. Lafferty and Gazada; blood cells - autoimmune haemolytic anaemia, B.C. Gilliland; systemic lupus erythematosus, M. Reichlin; antiphospholipid/cofactor syndromes, D. Alarcon-Segovia and A.R. Cabral; systemic sclerosis (scleroderma), M.E. Gershwin and C. Galperin; rheumatoid arthritis, J.S. Sundy and B.F. Haynes; Sjogren's syndrome, H.M. Moutsopoulos et al; autoimmune thyroid disease, A.P. Weetman; diabetes, A. Lemmark and S. Bieg; autoimmune gastritis and pernicious anaemia, B.-H. Toh et al; inflammatory bowel and coeliac disease, D.E. Elliott et al; autoimmune diseases of the liver, M.M. Manns and L. Obermayer-Straub; cutaneous autoimmune diseases, A. Diaz et al; autoimmune diseases of the central and peripheral nervous system, B.G.W. Arnason; autoimmune disease in the kidney, L.C. Racusen; autoimmune cardiovascular disease, B. Maisch; myasthenia gravis, D.B. Drachman; autoimmune diseases of muscle, P.N. Hollingsworth et al; autoimmune diseases of the testis and the ovary, K.S.K. Tung; vasculitis, J.C. Jennette and R.J. Falk; adrenal autoimmunity and the autoimmune polyglandular syndromes, types I-III, Addison's disease, hypoparathyroidism, hypophysitis, N.K. Maclaren et al; autoimmune diseases of the eye, M.H. Friedlaender and H. Fujishima; autoimmune diseases - cameos, curiosities and shadowlands, I.R. Mackay; aging and autoimmunity, M.E. Weksler et al; paraneoplastic autoimmune syndomes, G.J. Anhalt; autoimmune derangements in the acquired immunodeficiency syndrome, F. Silvestris et al; diagnosis of autoimmune disease, R.L. Dawkins et al; novel therapeutic approaches to autoimmunity, H. Wekerle and R. Hohfeld.
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Review quote

There is no doubt that the book is an indispensable source of information on autoimmunity for experimenters and for clinicians and it is highly recommended as a very stimulating textbook for advanced students studying biology and medicine. --IMMUNOLOGICAL INVESTIGATIONS The organization of the book is excellent... The entire gamut of autoimmune disease is discussed in a format that begins with basic mechanisms, extends through a diagnosis, and then on to therapy... This outstanding book is recommended for any and all physicians who care for patients with autoimmune diseases. It should serve as the primary source for fundamental and contemporary concepts of autoimmunity. --DOODY'S PUBLISHING REVIEWS
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