Part 1 Concepts and clinics of atrial fibrillation: from experiment to therapeutic innovation in atrial fibrillation and flutter; atrial functional anatomy; the pathology of drug resistant lone atrial fibrillation in eleven surgically treated patients; termination of atrial fibrillation by classic antiarrhythmic drugs, a paradox?; characteristics of patients with chronic atrial fibrillation and the prediction of successful DC electrical cardioversion. Part 2 Recent advances in the treatment of paroxysmal atrial fibrillation and flutter: pharmacological cardioversion of paroxysmal atrial fibrillation or atrial flutter to sinus rhythm; frugs after cardioversion to prevent relapses of chronic atrial fibrillation or flutter; episodic treatment of paroxysmal atrial fibrillation; an AICD for atrial fibrillation?; the "Corridor" operation as an alternative in the treatment of atrial fibrillation. Part 3 Why aggressive therapy in atrial fibrillation?: tachycardiomyopathy in patients with supraventricular tachycardia; sinus rhythm, the autonomic nervous system, and quality of life; atrial tachyarrhythmias following coronary bypass surgery - sympathetic mechanisms; management of paroxysmal atrial fibrillation and atrial flutter shortly after coronary artery bypass graft surgery; risk and prevention of embolism in atrial fibrillation; value of left atrial appendage flow velocities in patients with nonrheumatic atrial fibrillation and systemic embolism; management of atrial fibrillation - from palliation to intervention.