Arthritis Research
21%
off

Arthritis Research : Volume 1: Methods and Protocols

Edited by 

Free delivery worldwide

Available. Dispatched from the UK in 3 business days
When will my order arrive?

Not expected to be delivered to the United States by Christmas Not expected to be delivered to the United States by Christmas

Description

This is a compendium of data pertinent to the methods and protocols that have contributed to recent advances in molecular medicine in general, but to the molecular basis of rheumatic disease in particular. These volumes details novel technologies, some of which are still evolving and whose impacts are yet to be determined. Leaders in the field contribute to cover exciting and cutting edge topics. This compendium will be a valuable tool.show more

Product details

  • Hardback | 446 pages
  • 154.94 x 231.14 x 33.02mm | 816.46g
  • Humana Press Inc.
  • Totowa, NJ, United States
  • English
  • 2007 ed.
  • 17 Tables, black and white; 15 Illustrations, color; 99 Illustrations, black and white; XX, 446 p. 114 illus., 15 illus. in color.
  • 1588293440
  • 9781588293442
  • 2,482,976

Review quote

From the reviews: "...offers a comprehensive reference for the analysis of tissues relevant to arthritis research in brief chapters that emphasize how various analyses are performed. What separates this series from other references in this area is its ability to be brief but thorough in the discussion of technically challenging methods." -Doody's Book Review, Weighted Numerical Score:95 - 4 Stars "This multiauthored ... compendium of arthritis research methods and protocols provides pertinent practical information for the bench researcher as well as for the interested clinician. ... It is a worthwhile reference to have in the research laboratory ... . I enthusiastically recommend ... and believe this publication would have broad appeal to the rheumatologic community and to those in related specialties. ... I congratulate the authors on developing an excellent compendium of arthritis research ... ." (Robert J. Quinet, JAMA, April, 2008) "Arthritis Research: Methods and Protocols forms part of a book series on Methods in Molecular Medicine by Humana Press. ... Overall the books are extremely useful as both a practical guide and a reference text and are easy to understand. We would recommend the books to anyone with an interest in rheumatology research - basic scientists, clinicians and students ... ." (Leonie Taams and Hayley Evans, Immunology News, August, 2008)show more

Table of contents

Arthritis Research: Methods and Protocols, Volume I Andrew P. Cope, PhD I. Synovial Joint Morphology, Histopathology, and Immunohistochemistry 1. Imaging Inflamed Synovial Joints Ai Lyn Tan, Helen I. Keen, Paul Emery, and Dennis McGonagle 2. Arthroscopy as a Research Tool: A Review Richard J. Reece 3. Immunohitochemistry of the Inflamed Synovium Martina Gogarty and Oliver FitzGerald 4. In Situ Hybridisation of Synovial Tissue Stefan Kuchen, Christian A. See,ayer, Michel Neidhart, Renate E. Gay, and Steffen Gay 5. Subtractive Hybridization Jorg H. W. Distler, Oliver Distler, Michel Neidhart, and Steffen Gay 6. Laser Capture as a Tool for Analysis of Gene Expression in Inflamed Synovium Ulf Muller-Ladner, Martin Judex, Elena Neumann and Steffen Gay 7. Preparation of Mononuclear Cells from Synovial Tissue Jonathan T. Beech and Fionula M. Brennan 8. Quantitative Image Analysis of Synovial Tissue Pascal O. van der Hall, Maarten C. Kraan and Paul Peter Tak II. Cartilage Matrix and Bone Biology 9. Cartilage Histomorphometry Ernst B. Hunziker 10. Image Analysis of Aggrecan Degradation in Articular Cartilage with Formalin-Fixed Samples Barbara Osborn, Yun Bai, Anna H.K. Plaas, and John D. Sandy 11. In Situ Detection of Cell Death in Articular Cartilage Samantha N. Redman, Ilyas M. Khan, Simon R. Tew and Charles W. Archer 12. Measurement of Glycosaminoglycan Release from Cartilage Explants John S. Mort and Peter J. Roughley 13. Assessment of Collagenase Activity in Cartilage Tim E.Cawston and Tanya G. Morgan 14. Assessment of Gelatinase Expression and Activity in Articular Cartilage Rosalind M. Hembry, Susan J. Atkinson and Gillian Murphy 15. Analysis of MT1-MMP Activity Richard D. Evans and YoshifumiItoh 16. Analysis of TIMP Expression and Activity Linda Troeberg and Hideaki Nagase 17. Bone Histomorphology in Arthritis Models Georg Schett and Birgit Tuerk 18. Generation of Osteoclasts in vitro and Assay of Osteoclast Activity Naoyuki Takahashi, Nobuyuki Udagawa, Yasuhiro Kobayashi and Tatsuo Suda III. Cell Trafficking, Migration and Invasion 19. Isolation and Analysis of Large and Small Vessel Endothelial Cells Justin C. Mason, Elaine A Lidington and Helen Yarwood 20. Analysis of Flow Based Adhesion in vitro Oliver Florey and Dorian O. Haskard 21. Analysis of Leukocyte Recruitment in Synovial Microcirculation by Intravital Microscopy Gabriela Constantin 22. Angiogenesis in Arthritis - Methodological and Analytical Details Ursula Fearon and Douglas J. Veale 23. Analysis of Inflammatory Leukocyte and Endothelial Chemotactic Activity Zoltan Szekanecz and Alisa Koch 24. Acquisition, Culture and Phenotyping of Synovial Fibroblasts Sanna Rosengren, David L. Boyle and Gary S. Firestein 25. Genotyping of Synovial Fibroblasts: cDNA Array in Combination with RAP-PCR in Arthritis Elena Neumann, Martin Judex, Steffen Gay and Ulf Muller-Ladner 26. Gene Transfer to Synovial Fibroblast - Methods and Evaluation in the SCID Mouse Model Ingmar Meinecke, Edita Rutkauskaite, Antje Cinski, Ulf Muller-Ladner, Steffen Gay and Thomas Pap 27. In vitro Matrigel Fibroblast Invasion Assay Tanja C.A. Tolboom and Tom W.J. Huizinga 28. Culture and Analysis of Circulating Fibrocytes Timothy E. Quan and Richard Bucalashow more

Review Text

From the reviews: "...offers a comprehensive reference for the analysis of tissues relevant to arthritis research in brief chapters that emphasize how various analyses are performed. What separates this series from other references in this area is its ability to be brief but thorough in the discussion of technically challenging methods." -Doody's Book Review, Weighted Numerical Score:95 - 4 Stars "This multiauthored ... compendium of arthritis research methods and protocols provides pertinent practical information for the bench researcher as well as for the interested clinician. ... It is a worthwhile reference to have in the research laboratory ... . I enthusiastically recommend ... and believe this publication would have broad appeal to the rheumatologic community and to those in related specialties. ... I congratulate the authors on developing an excellent compendium of arthritis research ... ." (Robert J. Quinet, JAMA, April, 2008) "Arthritis Research: Methods and Protocols forms part of a book series on Methods in Molecular Medicine by Humana Press. ... Overall the books are extremely useful as both a practical guide and a reference text and are easy to understand. We would recommend the books to anyone with an interest in rheumatology research - basic scientists, clinicians and students ... ." (Leonie Taams and Hayley Evans, Immunology News, August, 2008)show more