Approaches to High Throughput Toxicity Screening

Approaches to High Throughput Toxicity Screening

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Description

An integrated approach to in vitro toxicology and ADME screening using new technologies and discussing how they might be applied to the safety assessment of new pharamceutical products in drug discovery.show more

Product details

  • Hardback | 200 pages
  • 210.82 x 271.78 x 17.78mm | 612.35g
  • Taylor & Francis Ltd
  • Informa Healthcare
  • New York, NY, United Kingdom
  • English
  • 15 black & white tables
  • 0748407529
  • 9780748407521

Table of contents

1. Introduction C.K. Atterwill, P. Goldfarb, and Wendy Purcell 2. Automation and Technology for HTS in Drug Development M. Banks 3. Cytotoxicity and Mechanistic Studies in High Throughput Toxicity Screening J. Fry 4. Gene Expression and its Applications to High Throughput Screens and Molecular Toxicology R. Burris, Robert T. Dunn II and S. Farr 5. Early Toxic Stressor Genes - Modulation and Screening Technologies C. Kind and T. Hammond 6. The Utility of Branched DNA (bDNA) Assays inshow more