Antiviral Research
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Antiviral Research : Strategies in Antiviral Drug Discovery

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Description

Captures the state of the science with twenty reviews that examine the latest in today's antiviral drug discovery efforts.




Presents the fundamental principles of antiviral agents and forecasts future possibilities.
Investigates novel enzyme and protein inhibitors.
Analyzes clinical aspects of viral infection with regard to treatment and toxicity.
Examines known and potential targets at all stages of viral development.
Serves as a resource for virologists, biochemists, pharmaceutical chemists, and other investigators.
Covers a broad range of viruses, including HIV-1, HSV, and HCV.








This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.
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Product details

  • Hardback | 412 pages
  • 215.9 x 279.4 x 22.86mm | 1,320g
  • Washington DC, United States
  • English
  • 1555814395
  • 9781555814397
  • 2,739,842

Table of contents

Table of Contents


1. Antiherpesviral DNA Polymerase Inhibitors

Donald M. Coen

2. Entry Inhibitors of Human Immunodeficiency Virus

Masanori Baba

3. Human Immunodeficiency Virus Type 1 Non-Nucleoside Reverse Transcriptase Inhibitors

Dirk Jochmans, Johan Vingerhoets, Eric Arnoult, Luc Geeraert, and Jerome Guillemont

4. Nucleoside Analogue Inhibitors of Human Immunodeficiency Virus Reverse Transcriptase

Jerome Deval and Matthias Goette

5. Integrase as a Novel Target for the Inhibition of Human Immunodeficiency Virus Type 1 Infection: Current Status and Future Perspectives

Linos P.R. Vandekerckhove, Frauke Christ, Zeger Debyser, Andrew Owen, David Back, Arnout Voet, Jonathan Schapiro, and Dirk Vogelaers

6. Human Immunodeficiency Virus Type 1 Tat and Rev as Potential Targets for Drug Development

Sergei Nekhai and Kuan-Teh Jeang

7. Inhibitors of the Human Immunodeficiency Virus Protease

Jorge L. Martinez-Cajas and Mark A. Wainberg

8. Hepatitis C Virus RNA-Dependent RNA Polymerase as a Target for Antiviral Drug Intervention: Non-Nucleoside Inhibitors

Yaya Liu, Yupeng He, and Akhteruzzaman Molla

9. Nucleoside Analog Inhibitors of Hepatitis C Viral Replication

Steven S. Carroll and Robert L. LaFemina

10. Antiviral Targets in Orthopoxviruses

Mark N. Prichard and Earl R. Kern

11. Influenza Virus Antiviral Targets

Gillian M. Air and Wayne J. Brouillette

12. Developments in the Search for Small Molecule Inhibitors for Treatment of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)

Dale L. Barnard and Yohichi Kumaki

13. Antiviral Treatment of Flaviviruses

Justin G. Julander

14. Clinical Aspects of Hepatitis C Virus Infection

David Durantel and Fabien Zoulim

15. Microbicides: Molecular Strategies for Prevention of Sexually Transmitted Viral Disease

Raina N. Fichorova

16. Phenotypic Susceptibility Assays for Human Immunodeficiency Virus Type 1

Neil T. Parkin, Eoin Coakley, and Christos J. Petropoulos

17. Metabolism of Antiviral Nucleosides and Nucleotides

Adrian S. Ray and Michael J. M. Hitchcock

18. Targeting the Interferon Response for Antiviral Therapy

Michael D. Robek

19. Toll-Like Receptors: Novel Molecular Targets for Antiviral Immunotherapy

Raymund R. Razonable, Albert J. Eid, and Martin Henault

20. New Herpes Simplex Virus Replication Targets

Sandra K. Weller



Afterword: Closing Thoughts

Robert L. LaFemina
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