Antidotes : Principles and Clinical Applications

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Antidotes provides up-to-date information on the development and clinical use of antidotes, their proposed mechanism of action, toxicity, availability and practical aspects of their clinical use. The antidotes discussed are primarily those either in current use, or under consideration or development. Some other compounds of mainly historical interest are also mentioned where appropriate. It contains information on the antidotal treatment of poisoning with compounds encountered not only in Western Europe, North America and Australia, but also developing countries. It covers source, shelf-life and instances where antidote administration complicates or compromises laboratory analyses.

There is no other single, published work that looks generally at antidotes, and it will prove invaluable to researchers, staff in poison information centers and A&E wards, drug information pharmacists, medical toxicologists and veterinarians. It will also be useful reading for medical students, trainee pharmacists, emergency physicians, ambulance staff and anesthetists.
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Product details

  • Paperback | 352 pages
  • 178 x 254 x 20.07mm | 612g
  • Informa Healthcare
  • New York, NY, United Kingdom
  • English
  • 45 b&w line drawings, 4pp colour illustrations, index
  • 0748409653
  • 9780748409655

Table of contents

General Introduction. Agents Used to Treat Poisoning with Metal Ions and Organometallic Compounds. Immunotherapy. Metabolic Antidotes. Pharmacological Antidotes. Antidotes to Carbon Monoxide, Cyanide and Hydrogen Sulphide. Antidotes to Chemical Warfare Agents. Antidotal Treatment of Paraquat Poisoning. Antidote Interference in Toxicological Analyses; Appendix 1: Which Antidote for Which Poison?; Appendix 2: Dosage and Dosage Form of Some Commonly Used Antidotes; Appendix 3: Decision Trees to Aid Treatment of Paracetamol Poisoning; Appendix 4: Guide to the Interpretation of Analytical Toxicology Results and Mass/Amount Concentration Conversion Factors for Some Metals and Trace Elements; Index.
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