The Anticancer Drugs

The Anticancer Drugs

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This is an up-to-date review of the pharmacology, mechanisms of action, development of resistance, and toxicity of cancer chemotherapeutic agents. A rationale for their clinical use, based on cancer cell biology, is given for each class of more

Product details

  • Hardback | 360 pages
  • 180 x 240 x 25.4mm | 598g
  • Oxford University Press Inc
  • New York, United States
  • English
  • Revised
  • 2nd Revised edition
  • 87 line drawings, bibliography
  • 019506738X
  • 9780195067385

Table of contents

Part I: Principles of Cancer Chemotherapy; The cancer problem; Some milestones in the development of cancer chemotherapy; Determinants of drug responsiveness; Resistance to anticancer drugs; Part II: The Anticancer Drugs; Antimetabolites; Covalent DNA binding drugs; Non-covalent DNA binding drugs; Inhibitors of chromatin function; Drugs affecting endocrine function; Part III: Clinical Cancer Chemotherapy; Choice of drugs for cancer chemotherapy; Part IV: New Directions in Cancer Chemotherapy; Anticancer drug development; Biological treatments of cancer; Potential targets for new anticancer more