Annual Reports in Medicinal Chemistry: v. 27

Annual Reports in Medicinal Chemistry: v. 27

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Intended for medicinal, pharmaceutical and organic chemists, this serial combines regular updates of significant areas of research in medicinal chemistry with emerging areas of biological science destined to affect the future discovery and development of new medicinal agents.
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Product details

  • Paperback | 373 pages
  • 177.8 x 230 x 19.05mm | 682g
  • Academic Press Inc
  • San Diego, United States
  • English
  • indexes
  • 012040527X
  • 9780120405275

Table of contents

Part 1 Agents: the decade of the brain, M. Williams; pharmacological intervention in sleep and circadian processes, J.D. Miller; advances in central serotoninergics, A.G. Romero and A.B. McCall; traumatic and ischemia/reperfusion injury to the CNS, J.M. McCall and J.A. Panetta; trophic factors and their receptors in the CNS, S. Rosenberg; antipsychotics, L.D. Wise and T.G. Heffner. Part 2 Cardiovascular and pulmonary agents: angiotensin/renin modulators, W.J. Greenlee and P.K.S. Siegl; EDRF, an emerging target for drug design, J.F. Kerwin, Jr; endogenous vasoactive peptides, A.M. Doherty; recent advances in antiarrhythmic therapy - potassium channel antagonists, M.G. Cimini and J.K. Gibson; future antithrombotic therapy, J.A. Jakubowski, et al; pulmonary and anti-allergy agents, R.T. Jacobs, et al. Part 3 Chemotherapeutic agents: antibacterial agents, targets, and approaches, M.J. Suto, et al; genetic engineering of antibiotic producing organisms, L. Katz and C.R. Hutchinson; inhibitors of angiogenesis, M.A. Mitchell and J.W. Wilks; recent advances in antifungal agents, J.F. Barrett and D.H. Klaubert; progress in antimicrobial peptides, S.W. Blondelle and R.A. Houghten; protein tyrosine kinases and cancer, E.M. Dobrusin and D.W. Fry. Part 4 Immunology, endocrinology, and metabolic diseases: monoclonal antibodies in therapy, G.A. Heavner; techniques for determining epitopes for antibodies and T-cell receptors, D.C. Benjamin and S.S. Perdue; potential therapeutic modifiers of the complement cascade, W.K. Hagmann and R.D. Sindelar; cytokine modulation as medicinal chemistry target, K. Cooper and H. Masamune; recent advances in the discovery and development of potential antidiabetic agents, J.R. Colca and S.P. Tanis. Part 5 Topics in biology: the role of homeobox genes in vertebrate embryonic development, K. Mahon and M. Jamrich; emerging therapies for cystic fibrosis, A.E. Smith; the guanylyl cyclase family of receptor/enzymes, H.-J. Fulle and D.L. Garbers; HIV vaccine development - from empiricism to medicinal chemistry, M.J. Glass and W.C. Kogg; inositol triphosphate receptors, S.K. Joseph. Part 6 Topics in drug design and discovery: macromolecular X-ray crystalloglraphy and NMR as tools for structure-based drug design, J.W. Erickson and S.W Fesik. Part contents.
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