Annual Reports in Medicinal Chemistry

Annual Reports in Medicinal Chemistry

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Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expectedto provide the basis for entirely new future therapies.
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Product details

  • Paperback | 340 pages
  • 166 x 248 x 20mm | 662.26g
  • Academic Press Inc
  • San Diego, United States
  • English
  • b&w illustrations, indexes
  • 0120405326
  • 9780120405329

Table of contents

Part 1 Central nervous system diseases, D.W. Robertson: recent advances in migraine therapy, T. Branchek and J.E. Audia; Alzheimer's disease - recent advances on the amyloid hypothesis, V. John et al; obesity - leptin-neuropeptide Y interactions in the control of body weight, D.R. Gehlert and M. Heiman; melatonin receptor ligands and their potential clinical applications, C.D. Mahle et al; corticotrophin-releasing hormone (CRH) receptors and the discovery of selective non-peptide CRH1 antagonists, P.J. Gilligan et al; recent advances in neurokinin receptor antagonists, S.G. Mills. Part 2 Cardiovascular and pulmonary diseases, A.M. Doherty: endothelin inhibitors, X.-M. Cheng et al; antithrombotics/serine proteases, W.C. Ripka and G.P. Vlasuk; leukotriene modulators as therapeutic agents in asthma and other inflammatory diseases, R.L. Bell et al; emerging opportunities in the treatment of atherosclerosis, C.M. Hayward and M.J. Bamberger. Part 3 Cancer and infectious diseases, J.J. Plattner: new approaches and agents to overcome bacterial resistance, J.M. Domagala and J.P. Sanchez; bacterial genomics and the search for novel antibiotics, L. Katz et al; resistance to antiretroviral drug therapy, A. Molla and W.E. Kohlbrenner; non-HIV antiviral agents, S.H. Krawczyk and N. Bischofberger; recent advances in antifungal agents, P.A. Lartey and C.M. Moehle; angiogenesis inhibitors, D. Powell et al; chemical inhibitors of cyclin-dependent kinases, K.G. Coleman et al. Part 4 Immunology, endocrinology and metabolic diseases, W.K. Hagmann: T lymphocyte potassium channel blockers, J.C. Kath et al; male contraception, D.W. Combs; new dermatological agents for the treatment of psoriasis, S. Nagpal and R.A.S. Chandraratna; selective cyclooxygenase-2 inhibitors, P. Prasit and D. Riendeau; growth hormone secretagogues, R.P. Nargund and L.H.T. Van der Ploeg. Part 5 Topics in biology, W.W. Wong: novel gene switches for the regulation of gene expression; agents that block TNF-I synthesis or activity, R.A. Black et al; nuclear orphan receptors - scientific progress and therapeutic opportunities, D.W. Robertson et al. Part 6 Topics in drug design and discovery, G.L. Trainor: discovery and identification of lead compounds from combinational mixtures, B.A. Beutal; electrospray mass spectrometric characterization of adducts between therapeutic agents and proteins, C. Fenselau; nonpeptide agonists for peptide receptors - lessons from ligands, E.E. Sugg; natural products research and pharmaceuticals in the 1990s, S.K. Wrigley and M.I. Chicarelli-Robinson; inhibition of cytochrome P-450 and implications in drug development, J.H. Lin and A.Y.H. Lu. Part 7 Trends and perspectives, J.A. Bristol: to market, to market - 1996, P. Galatsis.
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Review quote

":This series is one of the very few annual publications which justify the title of an absolute must for the pharmacologist, chemist, or physician who is interested in the chemistry of drug development. @soource:--ENZYMOLOGIA This book is strongly recommended for researchers, teachers, students, administrators--in short, anyone whose interests impinge on medicinal chemistry. In view of the work's documented reference value, it is a must for inclusion in the scientist's personal library. --JOURNAL OF MEDICINAL CHEMISTRY All topics are covered in sufficient depth, with extensive references, to allow either the specialist or the novice to be informed of the latest developments in a particular area of medicinal chemistry. --NORMAN GILMAN, Hoffmann-La Roche, Inc., in the JOURNAL OF PHARMACEUTICAL SCIENCES
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