Androgens in Health and Disease

Androgens in Health and Disease

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Description

Authoritative researchers and clinicians review our latest understanding of andrology in both basic science and clinical medicine. Topics range from explaining the biology of androgens-from several different perspectives-to illuminating their role in the development and modulation of physiologic systems. Authors demonstrate in a number of cases that testosterone can be a useful adjunct to the treatment of a variety of disease states. Other chapters consider important topics such as androgens use in athletes, the potential of androgens to improve physical function and quality of life in older men, and androgens as potential male contraceptives.
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Product details

  • Hardback | 448 pages
  • 178 x 254 x 32mm | 1,161.21g
  • Totowa, NJ, United States
  • English
  • 2003 ed.
  • 30 Illustrations, black and white; X, 448 p. 30 illus.
  • 1588290298
  • 9781588290298

Back cover copy

In recent years, medical researchers have demonstrated that androgens, both naturally occurring and synthetic, influence a myriad of physiological functions and can also be used therapeutically in a wide variety of clinical settings. In Androgens in Health and Disease, an authoritative panel of researchers and clinicians review our latest understanding of andrology in both basic science and clinical medicine. Topics range from explaining the biology of androgens-from several different perspectives-to illuminating their role in the development and modulation of physiologic systems. The authors demonstrate how testosterone can be a useful adjunct to the treatment of a variety of disease states, particularly those in which catabolism and loss of muscle mass occur. Other chapters consider important topics such as androgen use in athletes, the potential of androgens to improve physical function and quality of life in older men, and androgens as potential male contraceptives. Of special interest is a presentation of recent advances in understanding the physiological and clinical effects of androgen excess and androgen deficiency in women.
Authoritative and wide-ranging, Androgens in Health and Disease offers both researchers and practicing clinicians a comprehensive survey of how, why, and where androgens exert their effects, as well as their therapeutic roles in a broad range of diseases.
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Table of contents

I. General Andrology

Testosterone Synthesis, Transport, and Metabolism
Stephen J. Winters and Barbara J. Clark

Androgen Action
Terry R. Brown

Hypogonadism in Men: An Overview
Stephen R. Plymate

Dihydrotestosterone and 5a-Reductase: Normal Physiology and Inhibition
Paul R. Sutton, John K. Amory, and Richard V. Clark

Estrogen Action in Males: Insights Through Mutations in Aromatase and Estrogen-Receptor Genes
Jonathan Lindzey and Kenneth S. Korach

Alterations of Androgen Action Caused by Mutation of the Human Androgen Receptor
Michael J. McPhaul

Androgen Excess Disorders in Women
Richard S. Legro

Androgen Pharmacology and Delivery Systems
Christina Wang and Ronald S. Swerdloff

II. Androgen Effects on Physiologic Systems

Androgen Signaling in Prostatic Neoplasia and Hyperplasia
Marco Marcelli, Dolores J. Lamb, Nancy L. Weigel, and Glenn R. Cunningham

Androgens and Coronary Artery Disease
Frederick C. W. Wu and Arnold von Eckardstein

Androgens and Bone
Anne M. Kenny and Lawrence G. Raisz

Androgens and the Hematopoietic System
Shehzad Basaria and Adrian S. Dobs

Androgens and Body Composition
Laurence Katznelson

Androgens and Sexual Function in Men and Women
John Bancroft

Androgens and Cognition
Monique M. Cherrier and Suzanne Craft

III. Applied Andrology

Androgen Treatment of the Hypogonadal Male
Alvin M. Matsumoto

Androgens and Puberty
Erick J. Richmond and Alan D. Rogol

Androgens as Anabolic Agents
Shalender Bhasin, Linda J. Woodhouse, and Thomas W. Storer

Androgens and Male Contraception
John K. Amory

Androgens in Primary Care
Bradley D. Anawalt

Index
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