Part 1: Mechanisms of Substance P-Mediated Nociception and Opioid-Mediated Anti-ociception; A.I. Basbaum; Spinal Cord Neuronal Plasticity: Mechanisms of Persistent Pain following Tissue Damage and Nerve Injury; R. Dubner; Local Anaesthetic Pharmacology; D.H. Lambert; Pain Research and Basic Science - Pain and the Sympathetic Nervous System; P.G. Fine. Local Anesthesia Toxicity; D.H. Lambert. Effect of Post-operative Pain on Surgical Stress Response; H. Kehlet. Post-operative Pain Assessment and Choice of Methods of Treatment; L.B. Ready. Patient-Controlled Analgesia, part 1; Historical Perspective; P.F. White; Problems in the Management of Post-operative Pain; L.B. Ready; Patient-Controlled Analgesia, part 2 - an Update on its Clinical Usage; P.F. White; Organization and Operation of an Acute Pain Service; L.B. Ready; Role of Non-Opioid Analgesics in the Peri-Operative Period; G.P. Joshi, et al; Effect of Post-operative Pain on Surgical Outcome; H. Kehlet. Post-operative Pain Management in Children; D.C. Tyler. Pre-emptive Analgesia; H. Kehlet; The Spinal Route of Analgesia - Opioids and Future Options; M.J. Cousins, et al; Problems of Pain Measurement in Children; D.C. Tyler. Post Spinal Injury Pain - Mechanisms and Treatment Options; P.J. Siddal, M. Cousins; Prevention of Post Herpetic Neuralgia; A.P. Winnie; Opioids in the Management of Non-Malignant Pain; B.D. Hare. Epidural Steroids; A.P. Winnie; Multidisciplinary Evaluation and Management of Chronic Pain; T.M. Murphy; Managing the Unmanageable; T.M. Murphy; Neurolytic Blocks - Current Status in the Treatment of Cancer and Chronic Pain; M.J. Cousins; Chronic Pain Management in Children; D.C. Tyler; Alternative Drug Delivery Systems; J.B. Streisand.