Amphetamine and Its Analogs

Amphetamine and Its Analogs : Neuropharmacology, Toxicology and Abuse

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This work is intended for: researchers in drug abuse, particularly those studying the effects of stimulants and halucinogens; medicinal chemists; neuropharmacologists; psychopharmacologists; neuroscientists; pharmacologists; psychiatrists; and toxicologists. Non-technical description - Amphetamine (speed) is an exceedingly abused drug. This book describes how the drug works as a stimulant and hallucinogen, and examines the resultant effects. General description - Much of recent amphetamine research has focused on action mechanisms which may represent a liability for abuse. The research further points to apparent psychopathological disorders induced or precipitated by such abuse. Understanding action mechanisms may aid investigations into the pathophysiology and treatment of these disorders. The overviews contained in this book, which cover myriad aspects of the chemistry, pharmacology, behavior, and toxicology of amphetamine and its analogs, can assist researchers by summarizing past findings and indicating new directions of study.
The book: Presents advances in action mechanisms, toxicity, and psychopharmacology of amphetamine and its analogs; Examines amphetamine abuse in the United States and Japan; and Reviews literature from the mid-1970s to the present.
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Product details

  • Hardback | 491 pages
  • 162 x 238 x 30mm | 879.96g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0121733750
  • 9780121733759

Table of contents

History of use and abuse, A.K. Cho and D.S. Segal, chemistry and SAR, D.E. Nichols, metabolism of amphetamine and its derivatives, A.K. Cho and Y. Kumagai; neuropsychopharmacology - neurochemistry of amphetamine, R. Kuczenski and D.S. Segal, behavioral pharmacology of amphetamine, D.S. Segal and R. Kuczenski, neurochemistry of ring-substituted amphetamines, C.J. Schmidt, behavioral pharmacology of ring-substituted amphetamine, M.A. Geyer and C.W. Calloway, neurochemistry of halogenated amphetamines, R.W. Fuller and M.G. Henderson, mechanisms of abuse, A. McGregor and D.C.S. Roberts, neurochemical mechanisms of toxicity, J.W. Gibb et al, neurotoxicity of amphetamine and its analogs, L. Seiden et al, structural features of amphetamine neurotoxicity in the brain, K.J. Axt et al; use of abuse - use of abuse of ring-substituted amphetamine - clinical characteristics, G.A. Ricaurte and U.D. McCann, amphetamine psychosis, B. Angrist, use and abuse of amphetamines in Japan, K. Konuma; epidemiology - the epidemiology of amphetamines in the U.S., M. Miller and A.L. Hughes, the epidemiology of amphetamines in Japan, S. Fukui, present and future problems, C.R. Schuster and C.R. Hartel.
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