American Physiological Society Handbook of Physiology: Endocrinolgy Section 7

American Physiological Society Handbook of Physiology: Endocrinolgy Section 7

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With the many new techniques available in cellular and molecular biology, it has been possible to identify common patterns of activity in cells of the endocrine system. This volume provides and in-depth and up-to-date view of progress in cellular and molecular endocrinology. It deals with the conceptual fundamentals of receptor identification and structure, gene expression, signaling, and second messenger systems. It also describes newly appreciated concepts of receptor and gene regulation. And it covers physiological processes such as secretion, steroidogenesis, and apoptosis. The chapters are written by international authorities who are well-recognized for their contributions to the field of endocrinology. Combining physiology and molecular biology, the book will be of value to all basic endocrinologists and to clinicians interested in the underlying regulation of endocrine more

Product details

  • Hardback | 614 pages
  • 216 x 280 x 35mm | 1,972g
  • Oxford University Press Australia
  • OUP Australia and New Zealand
  • Melbourne, Australia
  • English
  • Subsequent
  • 22 black and white photographs and numerous line figures
  • 019510935X
  • 9780195109351

Table of contents

1. Cell Biology of Secretion; 2. Synthesis, Internalization, Recycling, and Regulation of Peptide Hormone Receptors; 3. Receptor-Mediated Endocytosis of Polypeptide Hormones by Vascular Endothelium; 4. Receptor Identification and Characterization; 5. Mediation of Secretory Cell Function by G-Protein Coupled Receptors; 6. G-Protein Coupled Receptors; 7. Desensitization of G Protein-Coupled Receptors; 8. Mammalian Gs-Stimulated Adenylyl Cyclases; 9. Calcium Signaling; 10. Phosphorylation in Cellular Signaling; 11. Phospholipid-Derived Second Messengers; 12. Membrane Receptor-Linked Disease States; 13. Cyclic AMP Inducible Transcription; 14. Targeted Delivery of Hormones to Tissues by Plasma Proteins; 15. Steroid Hormone Receptor Families; 16. The Roles of Cytochrome P450 in the Regulation of Steroidogenesis; 17. Structure and Location of Steroid Receptors; 18. Autocrine/Paracrine Intermediates in Hormone Action and Modulation of Cellular Responses to Hormones; 19. The Role of Pulsatility in Hormone Action; 20. Apoptosisshow more

About Dr. P. Michael Conn

P. Michael Conn is Professor and Director of Laboratory of Neuroendocrinology at Rockefeller more