American Medicine Volume 22

American Medicine Volume 22

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This historic book may have numerous typos and missing text. Purchasers can usually download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1916 edition. Excerpt: ...First of all, it is important to know that acidosis or alkali starvation results from perverted metabolism. The direct cause of acidosis is the abnormal production in the liver of diacetic and betaoxybutyric acids as a result of imperfect metabolism of fats and protein. Laboratory tests, it is true, have shown that acetone may be produced from carbohydrates in the test tube, but it has never been demonstrated that the ketone or acidosis bodies ever arise from carbohydrates in the human body. It is evident then, that from a therapeutic standpoint, the question of acidosis is of chief interest in relation to diet. All authorities now agree that the principal source of acidosis bodies is to be found in the fats. Acidosis appears immediately when the diet consists exclusively of fats and diminishes when food is entirely withdrawn. The acidosis bodies which appear in starvation are chiefly derived from the fats, since they diminish with the consumption of the fat reserve. It is also noticeable that acidosis is more marked in fat diabetics who are made to fast than in those who are lean. Zellner showed that the perfect oxidation of fats requires the simultaneous oxidation of carbohydrates. His experiments demonstrated that the proportions necessary for complete metabolism are one part by weight of carbohydrate to four of fat or one molecule of carbohydrate to three molecules of fatty acids, the equivalent of one calory of carbohydrate to nine calories of fat. M. H. Fischer has shown that acidosis may result from the accumulation of phosphoric and sulphuric acids as the result of a high protein diet. It has long been known that the introduction of carbohydrates either by ingestion, by hypodermoclysis or by intravenous injection is a more

Product details

  • Paperback | 550 pages
  • 189 x 246 x 28mm | 971g
  • United States
  • English
  • black & white illustrations
  • 1236983726
  • 9781236983725