Excerpt from The American Journal of the Medical Sciences, 1913, Vol. 145
I propose to present in broad outline the altered conditions of metabolism which occur in diabetes mellitus, and also to point out some of the indications for treatment which scientific investiga tions upon the metabolic disturbances have revealed.
The human body obtains its energy and nutrition from three types of foodstuffs: proteins, fats, and carbohydrates. For gen eral purposes of work, warmth, and nutrition all three groups serve well; the muscular tissues are, however, more specific in their requirements. The working cells of the muscles do not utilize each type of foodstuff alike; they find the sugars the most useful for their energy production. It is possible, but not very probable, that they can use other materials for the same purpose, but this in too slight an extent to make the substitution of any practical importance, and we may, therefore, for the present leave this possibility out of our calculations.
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