1. Policy: The Principles of Service Organisation and Practice; 2. Determinants of substance misuse; 3. Drug use in young people: short-term effects and long-term harms; 4. Young people, substances and harm; 5. Trends in substance use and abuse in young people; 6. Substance use and psychiatric commorbidity in children and adolescents; 7. The effectiveness of universal youth substance abuse prevention programmes; 8. Prevention of substance abuse: targeted approaches; 9. Treatment: course and outcome; 10. Legal and ethical issues in the treatment of children and young people; 11. Principles of assessment for adolescents with substance use disorders; 12. Assessment instruments and outcome measurement; 13. Biological markers (Drugs); 14. Assessment and management in the emergency department and the paediatric unit; 15. Brief alcohol interventions in young people: evidence and applicability; 16. Psychosocial interventions for young people with substance misuse disorders; 17. Empirical and clinical foundations of family-based interventions for adolescent substance abuse; 18. Pharmacological treatment of adolescent substance use disorder; 19. The role of primary care in management of substance use/abuse; 20. Integrates treatment of substance use disorders and co-occuring psychiatric disorders in adolescents.