Airways and Vascular Remodelling in Asthma and Cardiovascular Disease

Airways and Vascular Remodelling in Asthma and Cardiovascular Disease : Implications for Therapeutic Intervention

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Vascular diseases and asthma are two common diseases associated with considerable morbidity and mortality. Both are chronic, each has an inflammatory component, both are accompanied by remodelling of hollow tubes and both are amenable to early intervention. This book compares and contrasts research progress made in each area, including our current understanding of the pathophysiology involved and the results of large-scale multicentre trials.
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Product details

  • Hardback | 189 pages
  • 173.7 x 252.5 x 14.5mm | 527.51g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0125435401
  • 9780125435406

Table of contents

P.K. Jefferey, Structural Changes in Asthma.
T. Cocks, Changes in Vascular Reactivity in Artherogenesis: Markers of Endothial Cell Dysfunction Associated with Initiation of the Disease.
J.H. Campbell and G.R. Campbell, Vascular Smooth Muscle in Culture and its Relevance to the Study of Arthrogenesis.
V. Lindner, In Vivo Investigations of Vascular Smooth Muscle Remodelling.
M.J. Karnovsky and E.R. Edelman, Heparin/Heparan Sulphate Regulation of Vascular Smooth Muscle Cell Behaviour.
M.I. Kotlikoff, Regulation of Cytoplasmic Calcium in Airway Smooth Muscle Cells: Implications for Growth and Contractility.
J.G. Martin, Animal Studies with Drugs Affecting Airway Smooth Muscle Thickening.
M. Okazawa, P.D. Pare, J.C. Hogg, and R.K. Lambert, Mechanical Consequences of Remodelling of the Airway Wall.
A.J. Woolcock and J.K. Peat, Is Asthma a Reversible Disease?
L.A. Laitinen and A. Laitinen, Anti-Inflammatory Therapy of Asthma: Corticosteroids.
P. Konig, Anti-Inflammatory Therapy of Asthma: Non-Steroid Disease Modifying Agents.
P. Gresele, Design of Large Multicentre Therapeutic Trials.
The Relevance of the Cardiovascular Experience to the Design of Long Term Anti-Asthma Trials.
Discussion Section.
Subject Index.
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