Ageing, Sex and Deoxyribonucleic Acid Repair

Ageing, Sex and Deoxyribonucleic Acid Repair

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A book intended for molecular biologists, genetists, biochemists, and cell biologists researching aging, DNA repair, or sexual reproduction, as well as evolutionary biologists and gerontologists. The authors consider major unsolved problems in biology - why organisms age and why sexual reproduction exists. They provide an integrated explanation of ageing and sex based on current knowledge on DNA damage and repair.
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Product details

  • Hardback | 282 pages
  • 152.4 x 231.14 x 25.4mm | 476.27g
  • Academic Press Inc
  • San Diego, United States
  • English
  • index
  • 0120928604
  • 9780120928606

Table of contents

Major ideas and historical perspectives; DNA damage; immediate consequences of DNA damage; accumulation of DNA damage hypothesis of ageing applied to mammals; oxidative DNA damage as a potential major cause of ageing; additional evidence bearing on the DNA damage hypothesis of ageing; ageing in non-vertebrates with comparisons to aspects of ageing in mammals; DNA repair with emphasis on single-strand damages; DNA repair with emphasis on recombinational repair; meiosis and meiotic recombination; meiosis viewed as an adaptation for DNA repair; the selective advantage of outcrossing ; evolutionary aspects of sex; other theories of ageing and sex; overview - future directions, and implications.
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