Age-related Cataract

Age-related Cataract

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Description

World-wide, age-related cataract is the primary source of impaired vision in the elderly and humanity's major cause of blindness. This book represents the first analysis of all of the evidence bearing on the origin and consequences of this disease. The progressive deterioration of the human lens is described in unprecedented detail and examined from the perspective of the general principles of aging. Causal factors that have been implicated in cataract formation are then evaluated by the criterion of whether they are capable of producing the specific cellular and molecular changes which take place during aging and cataract formation. Three major causal factors - heat, oxygen, and ultraviolet radiation - account for all of the major features of cataract development. Epidemiological evidence concerning the distribution of age-related cataract among human populations shows that the prevalence of cataract is positively correlated with exposure to the ultraviolet radiation present in sunlight. The book concludes with a detailed proposal for a simple, safe, inexpensive, and practical program of prevention to reduce the prevalence of age-related cataract.show more

Product details

  • Hardback | 303 pages
  • 166.62 x 242.82 x 27.69mm | 616.88g
  • Oxford University Press Inc
  • New York, United States
  • English
  • 3 line illustrations, tables
  • 019506383X
  • 9780195063837

Table of contents

Preface: Age-related cataract: A global problem; PART I: EVALUATION OF THE EVIDENCE: General principles of aging; The structure of the lens and its defenses against spying; Age-related deterioration of the lens; General pro-aging factors in the lens; Special pro-aging factors in the lens; The aetiology of age-related cataract; The epidemiology of age-related cataract: Introduction and factors influencing sunlight exposure; Epidemiological studies: Solar radiation; Epidemiological studies: Nutrition and genetics; Epidemiological studies: Special factors; Summary and conclusions; PART II: PREVENTION OF AGE-RELATED CATARACT: A proposal for a program of prevention.show more