Advances in Pharmacology: Intracellular Signal Transduction v. 36

Advances in Pharmacology: Intracellular Signal Transduction v. 36

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Each volume of "Advances in Pharmacology" provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. Signal transduction is one of the most rapidly expanding fields in biomedical research. Written by renowned experts, "Intracellular Signal Transduction" provides up-to-date reviews on the role of protein phosphorylatin cascades, and the structure, regulation, and function of protein kinases and phosphatases. This volume was compiled in honour of Dr. Edwin Krebs' pioneering work in the field of signal transduction which earned him a Nobel Prize. It provides information in a variety of areas relating to the bio-chemistry, cell biology, and pharmacology of the signal transduction process in eukaryotic cells.
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Product details

  • Paperback | 222 pages
  • 159 x 241 x 19.05mm | 645g
  • Academic Press Inc
  • San Diego, United States
  • English
  • Ill.(some col.).figs.
  • 0125138059
  • 9780125138055

Table of contents

Regulation of somatostatin gene transcription by cAMP, M. Montminy et al; dissection of protein kinase cascades that mediate cellular response to cytokines and cellular stress, P. Cohen; cyclic nucleotide phosphodiesterases - gene complexity, regulation by phosphorylation and physiological implications, F. Burns et al; structural analysis of the MAP kinase ERK2 and studies of MAP kinase regulatory pathways, M.H. Cobb et al; novel protein phosphates which may participate in cell signalling, P.T.W. Cohen et al; protein tyrosine phosphates and the control of cellular signalling responses, N.K. Tonks; roles of the MAP kinase cascade invertebrate, T. Moriguchi et al; signal transductions of SH2/SH3 :ASH/GRB-2 downstream signallings, T. Takenawa et al; sphingolipid-dependent protein kinases, S.-I. Hakomori; g-protein-coupled receptor kinase - phosphorylation of muscarinic receptors and facilitation of receptor sequestration, T. Haga et al; molecular and cellular pharmacology of A calcium/calmodulin-dependent protein kinase II (CaM kinase II) inhibitor, KN-62 and proposal of CaM kinase phosphorylation cascades, H. Hidaka and H. Yokokura; intrasteric regulation of calmodulin-dependent protein kinases, B.E. Kemp et al; structure, regulation and function of calcium/calmodulin-dependent protein kinase I, M.R. Picciotto et al; gene expression and CREB phosphorylation induced by cAMP and Ca2+ in neuronal cells, M. Hagiwara et al.
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Review quote

Praise for the Series: "Recommended not only to pharmacologists but also to all those in related disciplines". --Nature "Superb reading material". --Journal of Pharmaceutical Sciences
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