Advances in Pathobiology and Management of Paget's Disease of Bone

Advances in Pathobiology and Management of Paget's Disease of Bone

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Advances in Pathobiology and Management of Paget's Disease of Bone presents an essential collection of up-to-date knowledge about the pathophysiology, genetics, and treatment of Paget's disease. It covers the comprehensive information related to clinical perspectives, epidemiology, genetics, environmental factors such as viral etiology, molecular abnormalities, complications such as osteosarcoma, and current and future treatment for Paget's disease. This book serves as a useful volume for basic scientists, graduate students, and practicing clinicians in understanding the pathobiology, etiology, and treatment of this disease.
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Product details

  • Paperback | 158 pages
  • 152 x 229 x 8.38mm | 270g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0128050837
  • 9780128050835

Table of contents

Chapter-1: Clinical Perspectives of Paget's disease of Bone, Tim Cundy, PhD

Chapter-2: Virus etiology of Paget's disease, Sakamuri V. Reddy, PhD

Chapter-3: Genetics of Paget's disease, Stuart H. Ralston,MD

Chapter-4; Developmental aspects of pagetic osteoclasts, G. David Roodman, MD

Chapter-5: Mutant SQSTM1/p62 signaling in Paget's disease of bone, Rob Layfield, PhD

Chapter-6: Early-onset Paget's disease and related disorders: gene mutations and their functional consequences, Miep H Helfrich

Chapter-7: Osteosarcoma in Paget's disease of bone, Marc F. Hansen, PhD

Chapter-8: Paget's disease of bone; Prognosis and complications, Jacques P. Brown, MD

Chapter-9: Treatment of Paget's disease, Ian R Reid, MD
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About Dr. Sakamuri V. Reddy

Sakamuri V. Reddy, Ph.D is currently Professor and Director of the Osteoclast Center in the Darby Children's Research Institute at the Medical University of South Carolina (MUSC), Charleston, SC, USA. Dr. Reddy is a member of the American Society of Bone and Mineral Research (ASBMR) and has over 24 years of experience in studying skeletal disorders and mechanisms of bone loss. His work is focused on osteoclast biology, Paget's disease of bone, cancer metastasis to bone, and microgravity-induced bone loss. Dr. Reddy received the Young Investigator award from ASBMR in 1992 and the Mitchell I. Rubin Research Award for distinguished scientific contributions to the advancement of medical sciences from MUSC in 2006. Dr. Reddy is presently an Academic Editor for PLOS ONE online journal and has served on the Editorial Board of the Journal of Bone and Mineral Research (JBMR). Additionally, he has served on several grant review panels at the National Institutes of Health (NIH), the Department of Defense (DOD), and other international scientific organizations. He has published nearly 100 peer-reviewed articles in the field of skeletal biology and diseases.
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