Advances in Lipid Research: v.26
Although sphingolipids constitute one of the most chemically and functionally diverse biomolecules, most of their biological functions and their regulations are not known. Recent findings have begun to explain various cell diseases, and why sphingolipids undergo changes in cell growth, differentiation and disease. "Advances in Lipid Research", Volumes 25 and 26 are thematically organized to emphasize the little-known biological functions of sphingolipids and their regulations. The importance of these compounds is revealed by their structural sophistication, the complete changes that they undergo with development, and their widespread utilization by eukaryotic organisms.
- Hardback | 371 pages
- 152.4 x 230 x 19.05mm | 722g
- 01 Oct 1993
- Elsevier Science Publishing Co Inc
- Academic Press Inc
- San Diego, United States
Table of contents
Part 1 Enzymes of sphingolipid metabolism: sphingomyelinases, M.W. Spence; neutral sphingomyelinase, S. Chatterjee; ceramidases - enzymology and metabolic roles, D.F. Hassler and R.M. Bell; sphingosine kinase - properties and cellular function, B.M. Buehrer and R.M. Bell; sphingosine-phosphate lyase, P.P. Van Veldhoven and G.P. Mannaerts. Part 2 Trafficking and topology of sphingolipid metabolism: intracellular transport of ceramide and its metabolites at the golgi complex - insights from short-chain analogs, R.E. Pagaan and A.G. Rosenwald; ganglioside metabolism - topology and regulation, K. Sandhoff and G. van Echten; truncated ceramide analogs as probes for sphingolipid biosynthesis and transport, D. Jeckel and F. Wieland; molecular approaches to studying the intracellular trafficking of glycosphingolipids, W.W. Young, Jr. Part 3 Functional and dysfunctional effects of sphingolipid metabolism: metabolic effects of inhibiting glucostylceramide synthesis with PDMP and other substances, N.S. Radin, et al; fumonisins and other inhibitors of de novo sphingolipid biosynthesis, A.H. Merrill, et al; extracellular sialidases, C.C. Sweeley; sphingolipids with inositolphosphate-containing head groups, R.L. Lester and R.C. Dickson; sphingomyelinase D - a pathogenic agent produced by bacteria and arthropods, A.P. Truett III and L.E. King. Part 4 Comparative and developmental biology: glycophingolipids of the invertebrata as exemplified by a cestode platyhelminth, taenia crassiceps and a dipteran insect, calliphora vicina, R.D. Dennis and H. Wiegandt; develo9pmental changes of glycosphingolipid composition of epithelia of rat digestive tract, J.F. Bouhours, et al.