Advances in Lipid Research: v.25

Advances in Lipid Research: v.25

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Although sphingolipids constitute one of the most chemically and functionally diverse biomolecules, most of their biological functions and their regulations are not known. Recent findings have begun to explain various cell diseases, and why sphingolipids undergo changes in cell growth, differentiation and disease. "Advances in Lipid Research", Volumes 25 and 26 are thematically organized to emphasize the little-known biological functions of sphingolipids and their regulations. The importance of these compounds is revealed by their structural sophistication, the complex changes that they undergo with development and their widespread utilization by eukaryotic organisms.
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Product details

  • Hardback | 340 pages
  • 152.4 x 230 x 19.05mm | 663g
  • Academic Press Inc
  • San Diego, United States
  • English
  • index, references
  • 0120249251
  • 9780120249251

Table of contents

A.H. Merrill, Jr., YA. Hannun, and R.M. Bell, Sphingolipids and Their Metabolites in Cell Regulation. Function of Sphingolipids and Sphingolipid Derived Products in Signal Transduction: Y.A. Hannun and R.M. Bell, The Sphingomyelin Cycle: A Prototypic Sphingolipid Signaling Pathway. Y.A. Hannun, L.M. Obeid, and R.A. Wolff, The Novel Second Messenger Ceramide: Identification, Mechanism of Action, and Cellular Activity. S. Mathias and R. Kolesnick, Ceramide: A Novel Second Messenger. R.T Dobrowsky and Y.A. Hannun, Ceramide-Activated Protein Phosphatase. Partial Purification and Relationship to Protein Phosphatase 2A. S. Spiegel, A. Olivera and R.O. Carlson, The Role of Sphingosine in Cell Growth Regulation and Transmembrane Signaling. R.J. Davis, Sphingolipid Regulation of the Epidermal Growth Factor Receptor. S Hakomori and Y. Igarashi, Gangliosides and Glycosphingolipids as Modulators of Cell Growth, Adhesions, and Transmembrane Signaling. Biologic and Pharmacologic Functions: P.H. Fishman, T. Pacuszka, and P.A. Orlandi, Gangliosides as Receptors for Bacterial Enterotoxins. C.A. Lingwood, Verotoxins and Their Glycolipid Receptors. P. Fredman, Glycosphingolipid Tumor Antigens. G. Tettamanti and L. Riboni, Gangliosides and Modulation of Neural Cells Function. H. Manev, A. Guidotti, and E. Costa, Protection by Gangliosides against Glutamate Excitotoxicity. A. Kendler and G. Dawson, The Role of Glycosphingolipids in Hypoxic Cell Injury. M. Saito, Bioactive Gangliosides Differentiation-Inducers for Hemopoietic Cells and Their Mechanism(s) of Actions.
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