Advances in Immunology: v. 64

Advances in Immunology: v. 64

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Description

This volume in the "Advances in Immunology" series presents recent findings related to the roles of proteasomes in the MHC class I-restricted antigen processing pathway and discusses recent observations and insights on V(D)J recombination. It also examines the structure, function and mechanisms of regulation of mammalian Ets transcription factors and the processes of b2m assembly and peptide loading and the involving molecules. Current concepts and enigmas of lymphocyte homing as well as a description of plasmacytomagenesis in mice and insights into the cellular and molecular biology of human plasma cell dyscrasias are included. In addition, the work provides a summary of the rationale for anti TNFa antibody therapy and its clinical effects.
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Product details

  • Hardback | 365 pages
  • 182.88 x 238.76 x 17.78mm | 566.99g
  • Academic Press Inc
  • San Diego, United States
  • English
  • colour and b&w illustrations, references, index
  • 012022464X
  • 9780120224647

Table of contents

K. Tanaka, Proteasomes and Antigen Processing. M. Gellert, Recent Advances in Understanding V(D)J. A.G. Bassuk and J.M. Leiden, The Role of Ets Transcription Factors in the Development and Function of Mammalian Immune System. T.H. Hansen and D.R. Lee, Mechanism of Class I Assembly with (2m and Loading with Peptide. M. Salmi and S. Jalkanen, How Do Lymphocytes Know Where to Go: Current Concepts and Enigmas of Lymphocyte Homing. N. Nishimoto, S. Suematsu, and T. Kishimoto, Plasma Cell Dyscraisas. M. Feldman, M.J. Elliott, J.N. Woody, and R.N. Maini, Anti TNF( Therapy of Rheumatoid Arthritis. Chapter References. Subject Index.
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Review quote

"The series which all immunologists need." --THE PHARMACEUTICAL JOURNAL "Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions." --SCIENCE "Deserves a permanent place in biomedical libraries as an aid in research and in teaching." --JOURNAL OF IMMUNOLOGICAL METHODS "A provocative and scholarly review of research." --JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION "Provides an extremely valuable source of reference and many stimulating ideas... the main repository of information in a rapidly developing subject." --THE LANCET "Provides unrivalled value in both academic and fiscal terms and should be purchased by hard pressed librarians as a major priority to be jealously defended." --JOURNAL OF MEDICAL MICROBIOLOGY "A very valuable serial publication... no serious student of immunology can afford to be without it." --ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
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