Advances in Genetics: Volume 32

Advances in Genetics: Volume 32

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Volume 32 of Advances in Genetics: Incorporating Molecular Genetic Medicine focuses on important and fast moving subjects in modern human genetics and medicine. This volume also marks the new collaboration with Associate Editors Dr. Theodore Friedmann and Dr. Francesco Giannelli. Chapter 1 considers the potential effectiveness and consequences of gene therapy on subjects over time. Chapter 2 discusses recent research on Gaucher's disease, the first disorder to demonstrate the clinical benefits of enzyme replacement therapy. Chapter 3 describes current findings on diabetes, a disease difficult to conquer due to its variety and its genetic and environmental causes. The major forms of hemophilia and the need for alternative therapies are discussed in Chapter 4. Chapter 5 presents hypercholesterolemia as a model for understanding the causes and treatments of human diseases on a molecular level. Chapter 6 probes the basic genetic defects behind phenylketonuria, as well as the possibilities for genetic correction. Chapter 7 covers the fascinating terminal structures of human chromosomes.
In the Foreword to Volume 32, Drs. Friedmann and Giannelli suggest: "Progress toward a thorough characterization of the human genome is stunningly rapid and exceeding many of its earliest expectations. Disease-related genes will be falling from the skies faster than we can understand them, and mechanisms responsible for the pathogenesis of disease will be illuminated more quickly and readily than ever before. "With comprehensive and timely reviews, Advances in Genetics incorporating Molecular Genetic Medicine offers with every volume further insight into this expanding field of medicine, supplementing the continued expert coverage of all other areas of genetics pioneered by Advances in Genetics.
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Product details

  • Hardback | 322 pages
  • 156 x 230 x 22mm | 621.43g
  • Academic Press Inc
  • San Diego, United States
  • English
  • index
  • 0120176327
  • 9780120176328

Review quote

Praise for the Series
"Outstanding both in variety and in the quality of its contributions."
From the Review of previous Volumes
"Can be highly recommended to geneticists, and biologists in general...will prove to be of high importance for the development of the science of genetics."
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About Jeffrey C. Hall

School of Medicine, University of California at San Diego, USA
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Table of contents

J.C. Hall and J.C. Dunlap, Foreword. T. Friedmann and F. Giannelli, Preface.
F.D. Ledley, After Gene Therapy: Issues in Long-Term Clinical Follow-Up and Care.
E. Beutler, Gaucher Disease.
T.S. Pillay,W.J. Langlois, and J.M. Olefsky, The Genetics of Non-insulin-Dependent Diabetes Mellitus.
P.M. Green, J.A. Naylor, and F. Giannelli, The Hemophilias.
T.P. Knecht and C.K. Glass, The Influence of Molecular Biology on our Understanding of Lipoprotein Metabolism and the Pathobiology of Atherosclerosis.
R.C. Eisensmith and S.L.C. Woo, Molecular Genetics of Phenylketonuria: From Molecular Anthropology to Gene Therapy.
N.J. Royle, The Proterminal Regions and Telomeres of Human Chromosomes.
Subject Index.
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