Advances in Cancer Research: v.64

Advances in Cancer Research: v.64

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Description

This volume contains reviews highlighting some of the most important achievements in understanding the molecular basis of cancer. Included are reviews on human papilloma virus and tumour suppressor gene products, the function of SH2 and SH3 domains in tyrosine kinase signal transduction, oncogene activation in mammary tumours, the phenotypes of polyoma middle T antigen in transgenic animals, and the role of protein kinase C and FCg receptors in neoplastic disease. Transgenic animal models for the study of molecular events in cancer are especially featured in these reviews.
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Product details

  • Hardback | 313 pages
  • 165 x 241 x 19.05mm | 626g
  • Academic Press Inc
  • San Diego, United States
  • English
  • index
  • 0120066645
  • 9780120066643

Table of contents

Interactons between papillomavirus proteins and tumour suppressor gene products; the retinoblastoma tumour suppressor protein; SH2 and SH3 domains in signal transduction; activation of the Src family of tyrosine kinases in mammary tumourigenesis; oncogenic properties of the middle T antigens of polyomaviruses; selective involvement of protein kinase C isozymes in differentiation and neoplastic development; FCgamma-receptors in malignancies - friends or enemies?; dissecting molecular carcinogenesis - development of transgenic mouse models by epidermal gene targetting.
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About George F. Vande Woude

Edited by George F. Vande Woude, and George Klein
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