Advances in Brain Cancer for Clinicians and Scientists

Advances in Brain Cancer for Clinicians and Scientists

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Advances in Brain Cancer for Clinicians and Scientists provides a rapid update for the busy clinician or scientist interested in learning about the latest advances in brain cancer research. This book is useful for scientists wishing to learn more about clinical advances, clinicians wanting to update themselves on scientific advances, or physicians or trainees who see patients irregularly, but still wish to stay up-to-date. The field of brain tumor research is exploding with new scientific information, and treatments are rapidly changing as new genetic discoveries and technological advances emerge. This book provides a single source for a unified update in this area that includes treatment protocols for brain tumor patients from many different perspectives.
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Product details

  • Paperback | 304 pages
  • 191 x 235mm
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0128026847
  • 9780128026847

Table of contents

Preface Contributors Introduction Basic Science I. Genetics of Adult Brain Tumors II. Genetics of Pediatric Brain Tumors Clinical Sciences Advances I. Surgery A. LITT Therapy B. Navigation C. Intraoperative Mapping D. Visualase II. Radiation A. Intensity-modulated Radiation Therapy III. Chemotherapy A. PCB for low-grade gliomas B. Temozolomide IV. Anti-vascular Therapy A. Phase III Avastin Trials V. Quality of Life A. Measuring and Improving Health-related Quality of Life VI. Imaging and Other Diagnostic Studies A. DTI Imaging B. MEG Results to Watch for I. Ipilimumab and Nivolumab Trials II. EGFRvIII CAR Trials III. Alliance Consortium Heatshock Protein Vaccine Trials IV. Celldex Therapeutics EGFRvIII Vaccine Trial
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About John H. Sampson

John H. Sampson, MD, PhD, MBA Dr. Sampson is the Robert H. and Gloria Wilkins Distinguished Professor of Neurosurgery and Chair of the Department of Neurosurgery for the Duke University Medical Center. He holds a leadership role in the Duke Cancer Institute's Neuro-Oncology Program and is a recognized leader in the surgical and experimental treatment of brain tumors with a focus on immunotherapy and drug delivery. He has authored more than 220 peer-reviewed publications in this field and serves on the Editorial Boards of the all the major journals in the field. Dr. Sampson has received special training in the surgical resection of very complex brain tumors. In addition, he has special training in the design and conduct of clinical trials. He did his research training under the internationally renowned scientist, Darell D. Bigner, and Nobel Laureate, Gertrude Elion. He currently focuses his clinical practice on treating patients with both benign and malignant brain tumors and divides his time between his clinical practice and an active research laboratory investigating new modalities of direct brain tumor infusion and immunotherapy. Dr. Sampson is internationally recognized in the field of neurosurgery and has received a number of national and international awards and grants in recognition of his expertise in neuro-oncology and especially in the area of immunotherapy for brain tumors. He developed a vaccine against a common mutation in brain tumors that was given Breakthrough Therapy Designation by the FDA after it was shown to extend survival in patients with the most malignant form of brain cancer. His work on another vaccine was also recently published in the journal Nature. His work has been highlighted on the CBS Evening News, 60 Minutes, The Wall Street Journal, and The Diane Rehm Show.
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