Adenosine Receptors in Neurology and Psychiatry: Volume 119

Adenosine Receptors in Neurology and Psychiatry: Volume 119

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This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on adenosine receptor science, providing insights useful for actual drug discovery/development in neurology and psychiatry areas.
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Product details

  • Hardback | 524 pages
  • 152 x 232 x 30mm | 999.98g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0128010223
  • 9780128010228

Table of contents

Adenosine Receptor Neurobiology: Overview
Jiang-Fan Chen, Chien-fei Lee and Yijuang Chern

Adenosine Receptor PET Imaging in Human Brain
Masahiro Mishina and Kiich Ishiwata

An Overview of Adenosine A2A Receptor Antagonists in Parkinson's Disease
Peter Jenner

Mode of Action of Adenosine A2A Receptor Antagonists as Symptomatic Treatment for Parkinson's Disease
Akihisa Mori

Adenosine Receptors and Dyskinesia in Pathophysiology
Masahiko Tomiyama

Clinical/Pharmacological Aspect of Adenosine A2A Receptor Antagonist for Dyskinesia
Tomoyuki Kanda and Shin-ichi Uchida

Interaction of Adenosine Receptors With Other Receptors from Therapeutic Perspective in Parkinson's Disease
Nicolas Morin and Therese Di Paolo

Effects of the Adenosine A2A Receptor Antagonist on Cognitive Dysfunction in Parkinson's Disease
Shin-ichi Uchida, Takako Kadowaki-Horita and Tomoyuki Kanda

Clinical Non-Motor Aspect of A2A Antagonist in PD Treatment
Masahiro Nomoto, Masahiro Nagai and Noriko Nishikawa

Adenosine Receptors and Huntington's Disease
Chien-fei Lee and Yijuang Chern

Adenosine Receptors and Epilepsy: Established Evidence and Perennial Potential
Susan A. Masino, Masahito Kawamura, Jr. and David N. Ruskin

Adenosine Receptor Control of Cognition in Normal and Disease
Jiang-Fan Chen

Adenosine Receptors in Cerebral Ischemia
Alessia Melani, Anna Maria Pugliese, and Felicita Pedata

Roles of Adenosine and its Receptors in Sleep-Wake Regulation
Zhi-Li Huang, Ze Zheng and Wei-Min Qu

Involvement of Adenosine A2A Receptors in Depression and Anxiety
Koji Yamada, Minoru Kobayashi and Tomoyuki Kanda

The Adenosine Neuromodulation System in Schizophrenia Daniel Rial, Diogo R. Lara and Rodrigo A. Cunha
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About Mori

Akihisa Mori, PhD., Deputy Director, Strategic Product Portfolio Department, Kyowa Hakko Kirin Co., Ltd. Tokyo, Japan. He has been leading adenosine A2A receptor science, intensively and extensively researching and discovering physiological functions of adenosine A2A receptor for brain motor control, and through such a tremendous scientific work, has also been working for a first-in-class Adenosine A2A receptor antagonist as new medication for Parkinson's Disease, for more than 20 years, from its discovery stage to filing both US and Japan NDA, which has been launched in Japan (2013). He was graduated from Faculty of Pharmaceutical Sciences, Kyoto University in 1985, and obtained Ph.D. degree from Graduate School of Medicine and Faculty of Medicine, The University of Tokyo in 1996. With number of publications in peer review journals in neuroscience field (e.g., J. Neuroscience, Neurology, J. Physiology, Annals of Neurology, British J Pharmacology etc.), he has given more than 20 lectures/podium talks for academia/universities and international conferences on various subjects (e.g., neurophysiology, adenosine receptor science, Parkinson's Disease, global drug development etc.) held not only in Japan but also in UK, Germany, Australia, Austria, and USA. In summary, he has greatly been contributing to translate from basic science of adenosine biology to practical drug development for adenosine receptor ligand in neurology area.
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