Von Willebrand Disease
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Von Willebrand Disease : Basic and Clinical Aspects

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Description

Von Willebrand Disease: Basic and Clinical Aspects provides an insight into all aspects of the condition. Since its discovery, von Willebrand disease has been extensively studied and the causative factor deficiency, the understanding of the condition and its treatment has greatly improved. This book summarizes recent research and will help to optimize the management of patients with von Willebrand disease. This valuable book describes the important and complex role of von Willebrand factor in hemostasis and thrombosis. In addition to the current understanding of its molecular biology, this book gives particular focus to the association between genetic variants of von Willebrand factor and different von Willebrand disease phenotypes. It also reviews the important area of the obstetric and gynecological manifestations of von Willebrand disease, as well as the treatment of acute bleeding. Written by an international team of contributors it describes the progress in, and difficulties of diagnosing phenotypes and genotypes. Molecular diagnosis of type 1, type 2 and its subgroups, and type 3 von Willebrand disease are presented as well as discussion of the potential future role of gene therapy. Von Willebrand Disease: Basic and Clinical Aspects is a valuable resource for hematologists in practice and in training, and specialists in thrombosis and hemostasis.

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Product details

  • Hardback | 268 pages
  • 188 x 248 x 20mm | 861.82g
  • John Wiley and Sons Ltd
  • Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)
  • Chicester, United Kingdom
  • English
  • 1405195126
  • 9781405195126
  • 1,160,454

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Author Information

Augusto B. Federici, University of Milan, Milan, Italy Christine A. Lee, Oxford Haemophilia & Thrombosis Centre, Oxford, UK Erik E. Berntorp, Lund University, Malmo, Sweden David Lillicrap, Queen's University, Kingston, ON, Canada Robert R. Montgomery, Medical College of Wisconsin; Milwaukee, WI, USA

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Review quote

"This book certainly helped to enhance my knowledge about von Willebrand disease and even prompted me to present a review of the disease to my colleagues. It is excellently written, appeals to a broad category of readers, and exceeds its stated objectives. I would definitely recommend the book to colleagues." (Doody's, 23 September 2011)

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Back cover copy

Von Willebrand Disease: Basic and Clinical Aspects provides an insight into all aspects of the condition. Since its discovery, von Willebrand disease has been extensively studied and the causative factor deficiency, the understanding of the condition and its treatment has greatly improved. This book summarizes recent research and will help to optimize the management of patients with von Willebrand disease. This valuable book describes the important and complex role of von Willebrand factor in hemostasis and thrombosis. In addition to the current understanding of its molecular biology, this book gives particular focus to the association between genetic variants of von Willebrand factor and different von Willebrand disease phenotypes. It also reviews the important area of the obstetric and gynecological manifestations of von Willebrand disease, as well as the treatment of acute bleeding. Written by an international team of contributors it describes the progress in, and difficulties of diagnosing phenotypes and genotypes. Molecular diagnosis of type 1, type 2 and its subgroups, and type 3 von Willebrand disease are presented as well as discussion of the potential future role of gene therapy. Von Willebrand Disease: Basic and Clinical Aspects is a valuable resource for hematologists in practice and in training, and specialists in thrombosis and hemostasis.

show more