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    Stem Cell Transplantation (Advances in Experimental Medicine and Biology) (Hardback) Edited by Carlos López-Larrea, Edited by Antonio Lopez Vazquez, Edited by Beatriz Suarez Alvarez

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    DescriptionOrgan transplantation has been the most important therapeutic advance in the last third of the 20th century. Its development has revolutionized medicine, as demonstrated by the fact that a large number of researchers in this field have been awarded Nobel Prizes. In the beginning of this century, we are witnessing with great expectations the emergence of a new field of medicine related to the arrival of a new player on the scene: "stem cells" and their potential use in regenerative medicine. This volume aims to cover important aspects of the various facets of organ transplantation and regenerative medicine, with leading specialists in these fields setting out their vision. We try to rigorously explain current and novel scientific research in these fields--areas which arouse great interest from society in general, due to their potential use in modern medicine for the treatment of a great number of diseases.

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    Stem Cell Transplantation
    Authors and contributors
    Edited by Carlos López-Larrea, Edited by Antonio Lopez Vazquez, Edited by Beatriz Suarez Alvarez
    Physical properties
    Format: Hardback
    Number of pages: 366
    Width: 178 mm
    Height: 254 mm
    Thickness: 15 mm
    Weight: 839 g
    ISBN 13: 9781461420972
    ISBN 10: 1461420970

    Warengruppen-Systematik des deutschen Buchhandels: 16960
    BIC E4L: HEA
    Nielsen BookScan Product Class 3: S6.1T
    B&T Book Type: NF
    B&T Modifier: Region of Publication: 01
    LC subject heading:
    Ingram Subject Code: SE
    Libri: I-SE
    B&T Merchandise Category: SCI
    B&T General Subject: 710
    LC subject heading:
    B&T Modifier: Text Format: 02
    B&T Modifier: Academic Level: 02
    LC subject heading:
    BISAC V2.8: MED026000, MED062000, SCI017000
    BIC subject category V2: MFGC
    DC22: 616.02774
    LC subject heading: ,
    LC classification: QH588.S83
    LC subject heading:
    BIC subject category V2: MJZ
    LC subject heading: , ,
    DC22: 616.02/774
    DC23: 616.02774
    LC classification: QH588.S83 S74279 2012, QH301-705, RC261-271
    Edition statement
    Illustrations note
    31 black & white illustrations, 17 colour illustrations, 26 black & white tables, biography
    Springer-Verlag New York Inc.
    Imprint name
    Springer-Verlag New York Inc.
    Publication date
    27 March 2012
    Publication City/Country
    New York, NY
    Author Information
    Carlos Lopez-Larrea is Professor of Immunology (Oviedo, Spain) and currently Head of the Department of Immunology at the Hospital Universitario Central de Asturias (Oviedo, Spain). He is a world expert on spondyloarthropathies (SpA), in particular MHC and genetic factors that influence the development of the disease. The main research interests of his group also currently include the study of epigenetic mechanisms involved in autoimmune diseases and the role of innate immunity in organ transplantation tolerance. He is a member of several international scientific organizations and board member of several scientific journals. He has published more than 150 international papers and book chapters related to immunology and spondylaorthropathies. Antonio Lopez-Vazquez, MD obtained the degree of Doctor of Medicine in the University of Navarra (Spain) in 1991. Currently, he is an Immunologist in the Department of Immunology of Hospital Universitario Central de Asturias in Oviedo (Spain). He specializes in histocompatibility and autoimmune diseases. Dr. Lopez-Vazquez's areas of interest investigation include organ transplantation, celiac disease and HCV infection. Beatriz Suarez-Alvarez is a research associate in the Histocompatibility Unit of the Immunology Service at the Hospital Universitario Central de Asturias (Oviedo, Spain). She obtained her PhD degree in Biology Sciences (Biochemistry and Molecular Biology) at the University of Oviedo, Spain. Her research project mainly focuses on the regulation of the Major Histocompatibility Complex during the differentiation of human embryonic and induced pluripotent stem cells to different cell types. Her research is based on the study of the epigenetic mechanisms involved in the regulation of genes of the immune system and their role in the development of immune tolerance during transplantation and autoimmune diseases.
    Table of contents
    The Frontiers of Organ Transplantation and Cell Therapy.- Organ Transplantation in the 21st Century.- Immunology and the Challenge of Transplantation.- Cellular Immunotolerance in the Transplant.- Immunosuppression in the Era of Biological Agents.- Transgenic Organs and Xenotransplants.- Cell and Tissue Therapy in Regenerative Medicine.- Characteristics of Adult Stem Cells.- Bone Marrow Transplantation Extends its Scope.- Biology of Stem Cells: The Role of Microenvironments.- Mobilization and Homing of Hematopoietic Stem Cells.- Great Promise of Tissue-Resident Adult Stem/Progenitor Cells in Transplantation and Cancer Therapies.- Multipotent Mesenchymal Stromal Cells: Clinical Applicat Ions and Cancer Modeling.- Neural Stem Cells and Transplantation Studies in Parkinson's Disease.- Biological Impact of Humanembryoni C Stem Cells.- Epigenetics of Embryoni C Stem Cells.- New Tools in Regenerative Medicine: Gene Therapy.- Therapeutic Cloning and Cellular Reprogramming.- Advances in Stem Cell Therapy.- Tissue Bioengineering and Artificial Organs.