• Pharmacology

    Pharmacology (Paperback) By (author) Humphrey P. Rang, By (author) M.Maureen Dale


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    DescriptionThis text describes the mechanisms by which drugs act and relates these to their overall pharmacological effects and clinical uses. This new edition emphasizes the chemical structures of those drugs for which knowledge of structure-activity relationships enhances appreciation of how the drugs act. It also includes new drugs, including drugs used not in therapy but in research. As regards other new material, the authors have taken into account new agents and also extensions of basic knowledge which presage further drug development. There are new chapters on 5-HT, on peptides as mediators, and on the control of lipoprotein metabolism. The references have been extended with the needs of postgraduate and university teachers in mind. Key points are included in relevant sections to help students' revision, while features retained from the first edition include the brief introductory summaries of relevant physiological and biochemical factors at the beginning of the chapter which form a basis for subsequent treatment.

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  • Full bibliographic data for Pharmacology

    Authors and contributors
    By (author) Humphrey P. Rang, By (author) M.Maureen Dale
    Physical properties
    Format: Paperback
    Number of pages: 968
    Width: 189 mm
    Height: 246 mm
    Thickness: 38 mm
    Weight: 1,840 g
    ISBN 13: 9780443041105
    ISBN 10: 0443041105

    BIC E4L: HEA
    Nielsen BookScan Product Class 3: S6.1T
    BIC subject category V2: MMG
    DC20: 615.1
    LC classification: RM300
    LC subject heading:
    BISAC V2.8: MED072000
    2, Revised
    Edition statement
    2nd Revised edition
    Illustrations note
    400 line drawings
    Elsevier Health Sciences
    Imprint name
    Publication date
    01 September 1991
    Publication City/Country
    Table of contents
    Part 1 General principles: how drugs act - general principles; how drugs act - molecular aspects; measurement in pharmacology; absorption, distribution and fate of drugs; individual variation and drug interaction. Part 2 Chemical mediators: chemical transmission and the autonomic nervous system; cholinergic transmission; adrenergic transmission; other peripheral mediators - 5-hydroxytryptamine and purines; peptides as mediators; local hormones, inflammation and allergy; drugs used to suppress inflammatory and immune responses. Part 3 Drugs affecting major organ systems: the heart; the circulation; control of lipoprotein metabolism; haemostasis and thrombosis; the respiratory system; the kidney; the gastro-intestinal tract; the endocrine system; the reproductive system; the haemopoietic system. Part 4 The central nervous system: chemical transmission and drug action in the central nervous system; general anaesthetic agents; anxiolytic and hypnotic drugs; neuroleptic drugs; drugs used in affective disorders; drugs used in treating motor disorders; analgesic drugs; central nervous system stimulants and psychotomimetic drugs; local anaesthetics and other drugs that affect excitable membranes. Part 5 Chemotherapy: basic principles of chemotherapy; cancer chemotherapy; antibacterial agents; antiviral drugs; antifungal drugs; antiprotozoal drugs; antihelminthic drugs. Part 6 General topics: non-therapeutic drugs - nicotine, alcohol, cannabis, cocaine, harmful affects of drugs.